Modulation of post-movement beta rebound by contraction force and rate of force development.
Modulation of post-movement beta rebound by contraction force and rate of force development.
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DOI：
10.1002/hbm.23189
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发表时间：
2016-07
影响因子：
4.8
通讯作者：
Brookes MJ
中科院分区：
文献类型：
--
作者：
Fry A;Mullinger KJ;O'Neill GC;Barratt EL;Morris PG;Bauer M;Folland JP;Brookes MJ
运动诱导的β节律调制是大脑中最强大的神经振荡现象之一。在运动的准备和执行阶段，观察到β振幅的损失[运动相关β降低（MRBD）]。随后是运动停止时高于基线的反弹[运动后β反弹（PMBR）]。这些影响已被广泛测量，最近的工作表明，它们可能具有重大意义。具体而言，它们有可能形成疾病生物标志物的基础，并已用于神经科学应用，从脑计算机接口到神经可塑性标记。然而，尽管MRBD和PMBR都具有强大的性质，但对现象本身的理解却很少。在这项研究中，我们将MRBD和PMBR在一个精心控制的等长腕关节屈曲范例，隔离两个基本的运动参数;力输出，和力发展率（RFD）。我们的研究结果表明，无论是改变力输出，也RFD有一个显着的影响MRBD。相反，PMBR被这两个参数改变。更高的力输出导致更大的PMBR振幅，并且更大的RFD导致振幅更高且持续时间更短的PMBR。这些发现表明，仔细控制运动参数可以系统地改变PMBR。此外，对于时间延长的运动，PMBR的持续时间可以超过7秒。这意味着准确的运动控制和明智的选择范式参数是至关重要的，在未来的临床和基础神经科学研究的感觉运动β振荡。《脑地图》37：2493-2511，2016年。© 2016 The Authors Human Brain Mapping由Wiley Periodicals，Inc出版
Movement induced modulation of the beta rhythm is one of the most robust neural oscillatory phenomena in the brain. In the preparation and execution phases of movement, a loss in beta amplitude is observed [movement related beta decrease (MRBD)]. This is followed by a rebound above baseline on movement cessation [post movement beta rebound (PMBR)]. These effects have been measured widely, and recent work suggests that they may have significant importance. Specifically, they have potential to form the basis of biomarkers for disease, and have been used in neuroscience applications ranging from brain computer interfaces to markers of neural plasticity. However, despite the robust nature of both MRBD and PMBR, the phenomena themselves are poorly understood. In this study, we characterise MRBD and PMBR during a carefully controlled isometric wrist flexion paradigm, isolating two fundamental movement parameters; force output, and the rate of force development (RFD). Our results show that neither altered force output nor RFD has a significant effect on MRBD. In contrast, PMBR was altered by both parameters. Higher force output results in greater PMBR amplitude, and greater RFD results in a PMBR which is higher in amplitude and shorter in duration. These findings demonstrate that careful control of movement parameters can systematically change PMBR. Further, for temporally protracted movements, the PMBR can be over 7 s in duration. This means accurate control of movement and judicious selection of paradigm parameters are critical in future clinical and basic neuroscientific studies of sensorimotor beta oscillations. Hum Brain Mapp 37:2493–2511, 2016. © 2016 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc