Prevalence of oligomenorrhea among women of childbearing age in China: A large community-based study
Prevalence of oligomenorrhea among women of childbearing age in China: A large community-based study
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中国育龄妇女月经稀发的患病率：一项大型社区研究
DOI：
10.1177/1745506520928617
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发表时间：
2020-06-01
期刊：
影响因子：
2.4
通讯作者：
Qiao, Jie
中科院分区：
文献类型：
--
作者：
He, Yilei;Zheng, Danni;Qiao, Jie
目的：了解我国育龄妇女月经稀发的患病率及相关特征。研究设计：2013年至2015年进行了一项大规模的基于社区的调查。共招募了来自中国9个省/直辖市的12，964名年龄在18-49岁的女性，在当地社区卫生中心进行健康筛查。结果测量包括临床病史、超声检查、激素和代谢参数。结果：中国育龄妇女月经稀发率为12.2%（1,579/12,964）。社会人口学因素和病史与月经过少有显著相关性（P < 0.05）。肥胖、痤疮、皮脂腺增生、棘皮症、卵巢肥大和多囊卵巢的患病率高于正常妇女，抗苗勒管激素、总睾酮和雄烯二酮的患病率也高于正常妇女（P < 0.05）。月经稀发组不孕率高于月经稀发组（17.2%，272⁄ 1，579），而非月经过少组（9.0%，1，024/11，385），在未避孕的妇女中，月经过少组的不孕率为32.5%（128/394），非月经过少组的不孕率为17.9%（400⁄ 2，240）。在月经过少组中，57.4%（156/272）的妇女接受了不孕症治疗，高于非月经过少组的36.1%（370/1,024）。结论：肥胖、痤疮、皮脂腺增生、棘皮症、卵巢较大和多囊卵巢形态与月经过少显著相关。月经过少组的抗苗勒管激素、总睾酮和雄烯二酮水平也有所增加。月经稀发者不孕症患病率和就诊率较高。
Objective: To investigate the prevalence and the related characteristics of oligomenorrhea among women within childbearing age in China. Study design: A large-scale community-based investigation was conducted from 2013 to 2015. A total of 12,964 women aged 18–49 years from 9 provinces/municipalities in China were recruited for healthcare screening in local community health centers. Outcome measures include clinical history, ultrasonographic exam, and hormonal and metabolic parameters. Results: Among women within childbearing age in China, the prevalence of oligomenorrhea was 12.2% (1,579/12,964). Both sociodemographic factors and medical history were significantly associated with oligomenorrhea (P < 0.05). In such women, the prevalence of obesity, acne, seborrhea, acanthosis, larger ovarian size, and polycystic ovarian morphology was higher when compared with normal women; the prevalence of anti-Mullerian hormone, total testosterone, and androstenedione (P < 0.05) was higher as well. The infertility rates of all women were higher in the oligomenorrhea group (17.2%, 272⁄1,579) than in the non-oligomenorrhea group (9.0%, 1,024⁄11,385), and among women without contraception, for the oligomenorrhea group, the infertility rate was 32.5% (128⁄394), and for the non-oligomenorrhea group, 17.9% (400⁄2,240). In the oligomenorrhea group, 57.4% (156/272) of the women underwent treatments for infertility, which was higher than the non-oligomenorrhea group 36.1% (370/1,024). Conclusions: Obesity, acne, seborrhea, acanthosis, larger ovarian size, and polycystic ovarian morphology were significantly associated with oligomenorrhea. The increase of anti-Mullerian hormone, total testosterone, and androstenedione level was also demonstrated in the oligomenorrhea group. Higher prevalence of infertility and medical treatment rate was observed in women with oligomenorrhea.