SURVIVAL AFTER HIGH OR LOW LIGATION OF THE INFERIOR MESENTERIC-ARTERY DURING CURATIVE SURGERY FOR RECTAL-CANCER
SURVIVAL AFTER HIGH OR LOW LIGATION OF THE INFERIOR MESENTERIC-ARTERY DURING CURATIVE SURGERY FOR RECTAL-CANCER
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DOI：
10.1097/00000658-198412000-00010
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发表时间：
1984-01-01
影响因子：
9
通讯作者：
NICHOLLS, RJ
中科院分区：
文献类型：
--
作者：
PEZIM, ME;NICHOLLS, RJ
为了确定直肠和直肠乙状结肠癌手术期间肠系膜下动脉高位结扎是否比低位结扎具有显着的 5 年生存优势，我们对 1370 名患者的结果进行了审查。 784 名患者的肠系膜下动脉在左结肠动脉起点下方结扎（低位结扎），586 名患者的肠系膜下动脉在左结肠动脉起点上方结扎（高位结扎）。两组肿瘤组织学分级的分布和静脉侵犯的发生率相似。五年随访完成率为 98.5%。对于 Dukes A、B、C 整体或 C1 肿瘤患者，无论进行低位结扎还是高位结扎，粗略或年龄校正的 5 年生存率没有差异。希望确定受益于高位结扎的人群。 C1 患者根据肿瘤位置和受累淋巴结数量进一步分组。在这样的亚组中没有观察到任何显着的高连接优势。未发现肠系膜下动脉高位结扎可以改善直肠癌或直肠乙状结肠癌患者的 5 年生存率。
In an attempt to determine whether high ligation of the inferior mesenteric artery during surgery for cancer of the rectum and rectosigmoid confers any significant 5-yr survival advantage over low ligation, the outcome of 1370 patients was reviewed. There were 784 patients in whom the inferior mesenteric artery was ligated below the origin of the left colic artery (low ligation) and 586 in whom it was ligated above this level (high ligation). The distribution of histologic grades of the tumors and incidence of venous invastion were similar in both groups. Five-year follow-up was complete in 98.5%. No difference in the crude or age-corrected 5-yr survival was found for patients with Dukes A, B, C overall, or C1 tumors whether having had a low or high ligation. In hopes of identifying a population that benefited from high ligation. C1 patients were further subgrouped according to tumor location and number of involved lymph nodes. In no such subgroup was any significant high ligation advantage seen. High ligation of the inferior mesenteric artery was not found to improve 5-yr survival in patients with cancer of the rectum or rectosigmoid.