Follow-Up of Pulmonary Hypertension With Echocardiography
Follow-Up of Pulmonary Hypertension With Echocardiography
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DOI：
10.1016/j.jcmg.2016.02.022
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发表时间：
2016-06-01
影响因子：
14
通讯作者：
Marwick, Thomas H.
中科院分区：
文献类型：
--
作者：
Wright, Leah M.;Dwyer, Nathan;Marwick, Thomas H.
Individual patient response to effective therapies for pulmonary hypertension (PAH) is variable and difficult to quantify. Consequently, management decisions regarding initiation and continuation of therapy are highly dependent on the results of investigations. Registry data show that changes in cardiac index, mean right atrial pressure, and mean pulmonary artery pressure have the greatest influence on survival. It is recognized that pulmonary artery pressure (PASP) responses to PAH-specific drugs are heterogeneous. However, follow-up testing is strongly focused on assessing changes in PASP and functional status (6-min walk). The goals of therapy, which should be highlighted in follow-up imaging, include not only reduction of PASP, decrease in pulmonary vascular resistance, and improvements in right ventricular function, cardiac output, and tricuspid regurgitation. This paper reviews the echocardiographic follow-up of pulmonary hypertension, and especially focuses on right ventricular function-a major determinant of outcome, for which reliable echocardiographic assessment has become more feasible. (C) 2016 by the American College of Cardiology Foundation.
