Isolation and characterization of Xenorhabdus nematophila transposon insertion mutants defective in lipase activity against Tween.
Isolation and characterization of Xenorhabdus nematophila transposon insertion mutants defective in lipase activity against Tween.
复制标题
对吐温脂肪酶活性有缺陷的嗜线虫致病杆菌转座子插入突变体的分离和表征。
DOI：
10.1128/jb.00173-09
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发表时间：
2009
影响因子：
3.2
通讯作者：
Goodrich-Blair,Heidi
中科院分区：
文献类型：
--
作者：
Richards,GregoryR;Vivas,EugenioI;Andersen,AaronW;Rivera-Santos,Delmarie;Gilmore,Sara;Suen,Garret;Goodrich-Blair,Heidi
我们鉴定出了脂肪酶活性缺陷的嗜酸乳杆菌转座子突变体。其中一个突变，inyigL，一个保守的基因的未知功能，导致对Manduca sextainsects的毒力减弱。我们讨论脂肪酶的生产，YigL，和特定的代谢途径之间可能的联系。
We identifiedXenorhabdus nematophilatransposon mutants with defects in lipase activity. One of the mutations, inyigL, a conserved gene of unknown function, resulted in attenuated virulence againstManduca sextainsects. We discuss possible connections between lipase production, YigL, and specific metabolic pathways.