Modeling and test of fiber-optics fast SPR sensor for biological investigation
Modeling and test of fiber-optics fast SPR sensor for biological investigation
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DOI：
10.1016/j.sna.2004.10.036
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发表时间：
2005-04-13
影响因子：
4.6
通讯作者：
Kawakami, Y
中科院分区：
文献类型：
--
作者：
Micheletto, R;Hamamoto, K;Kawakami, Y
表面等离子体共振（SPR）传感器是一种高灵敏度的光学系统，常用于有机样品的研究或其他基础研究课题。通常，SPR传感器基于其上沉积有薄层金的棱镜。这些传感器通常是全尺寸的光学设备，笨重且难以运输。为了使SPR传感器更灵活、更轻便，我们开发了一种基于金属涂层光纤的新型系统。它的光学和传感特性进行了研究，使用的分析方法，并与数值蒙特卡罗方法的帮助下。我们将描述一个实际的传感器的制造和实现传感测试的实验装置的发展。我们通过实验证明了光纤传感器检测2 nm十八烷硫醇有机膜的存在的能力;测量显示出良好的S/N比和几秒时间的快速响应。据我们所知，我们的系统是迄今为止实现的最快的SPR传感器。(c)2004 Elsevier B. V.保留所有权利。
Surface plasmon resonance (SPR) sensors are high sensitive optical system often used for investigations on organic samples or in general for other fundamental research topics. Normally a SPR sensor is based on a prism on which a thin layer of gold has been deposited. These sensors are usually full-size optical devices, heavy and difficult to transport. In the effort to miniaturize and make more flexible and light SPR sensors we developed a novel system based on a metal-coated optical fiber. Its optical and sensing characteristics were studied using an analytical approach and with the aid of a numerical Monte Carlo method. We will describe the fabrication of an actual sensor and the development of an experimental setup realized for sensing tests. We experimentally demonstrated the ability of the optical fiber sensor to detect the presence of a 2 nm octadecane thiol organic film; measurements showed good S/N ratio and rapid response of few seconds time. As far as we know, our system is the fastest SPR sensor realized so far. (c) 2004 Elsevier B.V. All rights reserved.