Neural circuits controlling cardiorespiratory responses: baroreceptor and somatic afferents in the nucleus tractus solitarius.
Neural circuits controlling cardiorespiratory responses: baroreceptor and somatic afferents in the nucleus tractus solitarius.
复制标题
控制心肺反应的神经回路：孤束核中的压力感受器和体细胞传入。
DOI：
10.1046/j.1440-1681.2002.03613.x
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发表时间：
2002
影响因子：
2.9
通讯作者：
Potts,JeffreyT
中科院分区：
文献类型：
--
作者：
Potts,JeffreyT
1. 大量的外周受体向中枢神经系统（CNS）提供感觉信号，在运动过程中协调自主运动向心血管器官（如心脏和外周血管）的流出。2. 这种感觉输入大部分是由位于血管（动脉压力感受器）和骨骼肌（骨骼肌麦角感受器）的心血管受体介导的。3. 一些髓核是心血管受体的靶点，包括孤束核（NTS）。4. 在本综述中，研究了NTS中动脉压力感受器和体感感受器传入信号之间的相互作用，同时特别强调了处理这些信号的神经化学和电生理机制。来自麻醉动物的数据，以及来自创新工作的心-脑干准备，将说明gaba能传递在运动过程中尾侧NTS压力感受器信号的潜在作用。
1. A vast array of peripheral receptors provide the central nervous system (CNS) with sensory signals that coordinate autonomic motor outflow to cardiovascular organs, such as the heart and peripheral vasculature, during locomotion. 2. Much of this sensory input is mediated by cardiovascular receptors located in blood vessels (arterial baroreceptors) and skeletal muscle (skeletal muscle ergoreceptors). 3. Several medullary nuclei are targets for cardiovascular receptors, including the nucleus tractus solitarius (NTS). 4. In the present review, the interaction between arterial baroreceptor and somatosensory receptor afferents in the NTS is examined while placing particular emphasis on the neurochemical and electrophysiological mechanisms involved in processing these signals.5. Data from anaesthetized animals, as well as from an innovative working heart–brainstem preparation, will illustrate the potential role of GABAergic transmission on baroreceptor signalling in the caudal NTS during locomotion.