Platelet membrane microparticles in blood bank fresh frozen plasma and cryoprecipitate.
Platelet membrane microparticles in blood bank fresh frozen plasma and cryoprecipitate.
复制标题
DOI：
10.1182/blood.v68.1.307.bloodjournal681307
复制
发表时间：
1986-07
期刊：
影响因子：
20.3
通讯作者：
J. George;E. Pickett;R. Heinz
中科院分区：
文献类型：
--
作者：
J. George;E. Pickett;R. Heinz
Cryoprecipitate has been demonstrated to correct the bleeding abnormality of patients with some congenital (storage pool disease) and acquired (uremia) platelet abnormalities, but the reason for this effect is unknown. We found significant platelet contamination in plasma harvested to prepare fresh frozen plasma and cryoprecipitate. The platelet membrane microparticles produced by freezing and thawing of the plasma were highly concentrated in cryoprecipitate and may contribute to its therapeutic effect.
