Characterization of graft polymers for biomedical applications.
Characterization of graft polymers for biomedical applications.
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用于生物医学应用的接枝聚合物的表征。
DOI：
10.1002/jbm.820140512
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
Ratner,BD
中科院分区：
文献类型：
--
作者：
Ratner,BD
接枝共聚物体系经常被建议用于生物医学应用。由于接枝过程改变了聚合物的性质，因此彻底的表征是至关重要的，特别是对这些共聚物的表面区域。本文简要讨论了接枝过程，然后介绍了接枝共聚物的表征方法。重量表征，热力学测量，表面化学分析，和表面地形分析的详细考虑。此外，还讨论了材料表征与预测和理解生物相容性反应的相关性。所描述的大多数分析技术适用于所有生物材料，并应考虑用于将与生物系统接口的材料的常规表征。
Graft copolymer systems have frequently been suggested for biomedical applications. Since the properties of polymers are altered by the grafting process, thorough characterization is critical, particularly for the surface region of these copolymers. This review briefly discusses the grafting process and then describes characterization procedures for graft copolymers. Gravimetric characterization, thermodynamic measurements, surface chemistry analysis, and surface topographical analysis are considered in detail. Also, the relevance of materials characterization for predicting and understanding the biocompatibility response is discussed. Most of the analytical techniques described are applicable to all biomaterials and should be considered for the routine characterization of materials which will be interfaced with biological systems.