Dietary patterns and endometrial cancer risk in the California Teachers Study cohort
Dietary patterns and endometrial cancer risk in the California Teachers Study cohort
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DOI：
10.1007/s10552-015-0552-1
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发表时间：
2015-04-01
影响因子：
2.3
通讯作者：
Horn-Ross, Pamela L.
中科院分区：
文献类型：
--
作者：
Canchola, Alison J.;Lacey, James V., Jr.;Horn-Ross, Pamela L.
关于饮食模式和子宫内膜癌风险的作用的信息是有限的。我们调查了饮食模式是否与加州教师研究队列中女性的子宫内膜癌风险相关。在75,093名符合条件的女性中，937名在1995年至2011年期间患上了浸润性子宫内膜癌。采用多变量考克斯回归分析，估计与主成分因子分析确定的五种饮食模式相关的相对风险（RR）和95%置信区间（CI）：“植物性”、“高蛋白/高脂肪”、“高碳水化合物”、“种族”和“沙拉和葡萄酒”。这些饮食模式与子宫内膜癌风险总体上无关（RR = 0.91，95%CI：0.72，1.15，对于“植物性”饮食模式的最高和最低五分位数）或绝经状态和激素治疗使用。饮食模式似乎与子宫内膜癌风险无关。
Information on the role of dietary patterns and endometrial cancer risk is limited. We investigated whether dietary patterns are associated with endometrial cancer risk among women in the California Teachers Study cohort.Among 75,093 eligible women, 937 developed invasive endometrial cancer between 1995 and 2011. Multivariate Cox regression was performed to estimate relative risks (RR) and 95 % confidence intervals (CI) associated with five dietary patterns identified by principal components factor analysis: "plant-based," "high protein/high fat," "high carbohydrates," "ethnic," and "salad and wine."These dietary patterns were not associated with endometrial cancer risk overall (RR = 0.91, 95 % CI: 0.72, 1.15 for the highest vs. lowest quintile of the "plant-based" dietary pattern) or by menopausal status and hormone therapy use.Dietary patterns do not seem to be associated with endometrial cancer risk.