Integration of motor and visual information in the parietal area 5 during locomotion
Integration of motor and visual information in the parietal area 5 during locomotion
复制标题
DOI：
10.1152/jn.01147.2002
复制
发表时间：
2003-08-01
影响因子：
2.5
通讯作者：
Sirota, MG
中科院分区：
文献类型：
--
作者：
Beloozerova, IN;Sirota, MG
顶叶皮质同时接受视觉和运动相关的信息，被认为是视觉-运动协调的场所之一。这项研究首次表征了在需要视觉-运动协调的条件下运动时顶区5区神经元活动中视觉和运动信息的整合。猫在平坦的表面行走时，神经元的活动被记录下来--这是一种不需要视觉运动协调的任务(平面运动)，沿着水平梯子或一系列障碍行走--一项需要视觉运动协调的任务，以便在沿着前进方向不同的表面上准确地放置脚(梯子和障碍运动)，以及沿着狭窄的路径行走--一项任务需要视觉运动协调在沿着前进方向均匀的表面上(狭窄运动)。在平坦运动中，66%的神经元的活动受到步进节律的调节，通常是一个周期一个峰值。在阶梯运动和屏障运动过程中，节律性活动神经元的比例显著增加，调制变得更强，大多数神经元每个周期有两个活动高峰。然而，在狭窄运动中，神经元的活动与平坦运动时相似。我们的结论是，在运动过程中，顶区5整合了两种类型的信息：关于基本运动机制活动的信号和关于表面沿前进方向的异质性的信号。我们在这里描述了这两种类型的信息在移动过程中的整合模式。
The parietal cortex receives both visual- and motor-related information and is believed to be one of the sites of visuo-motor coordination. This study for the first time characterizes integration of visual and motor information in activity of neurons of parietal area 5 during locomotion under conditions that require visuo-motor coordination. The activity of neurons was recorded in cats during walking on a flat surface-a task with no visuo-motor coordination required (flat locomotion), walking along a horizontal ladder or a series of barriers-a task requiring visuo-motor coordination for an accurate foot placement on surface that is heterogeneous along the direction of progression (ladder and barriers locomotion), and walking along a narrow pathway-a task requiring visuo-motor coordination on surface homogeneous along the direction of progression (narrow locomotion). During flat locomotion, activity of 66% of the neurons was modulated in rhythm of stepping, usually with one peak per cycle. During ladder and barrier locomotion, the proportion of rhythmically active neurons significantly increased, their modulation became stronger, and the majority of neurons had two peaks of activity per cycle. During narrow locomotion, however, the activity of neurons was similar to that during flat locomotion. We concluded that, during locomotion, parietal area 5 integrates two types of information: signals about the activity of basic locomotion mechanisms and signals about heterogeneity of the surface along the direction of progression. We describe here the modes of integration of these two types of information during locomotion.