Flexible delivery of Er:YAG radiation at 2.94 µm with novel hollow-core silica glass fibres: demonstration of tissue ablation
Flexible delivery of Er:YAG radiation at 2.94 µm with novel hollow-core silica glass fibres: demonstration of tissue ablation
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使用新型空心石英玻璃纤维灵活传输 2.94 µm Er:YAG 辐射：组织消融演示
DOI：
10.1117/12.2002430
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发表时间：
2013
期刊：
影响因子：
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通讯作者：
Urich A
中科院分区：
文献类型：
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作者：
Urich A
在这项工作中，我们介绍了工作在2.94μm的高能Er：YAG光脉冲通过空芯负曲率光纤(HC-NCF)和空芯光子晶体光纤(HC-PCF)的传输及其在生物组织消融中的应用。在最近开发的HC-NCF光纤中，激光辐射被限制在中空芯中，并受到反谐振或反射原理(也称为ARROW)的限制。这两种纤维都是由熔融二氧化硅制成的，具有很高的机械和化学耐久性，是生物惰性的，产生的纤维具有柔韧性，便于处理和最小限度的侵入性操作。HC-NCF结构只由一个相对较大的核心周围的一环毛细管组成，随后是一个保护外层，因此与传统的HC-PCF相比，预制件相对容易制造。在2.94μm处测得HC-NCF和HC-PCF的衰减率分别为0.06和1.2dB/m。两种光纤都具有单模输出光束轮廓，这对于外科应用是有利的，因为在光纤移动期间保持光束轮廓。我们演示了高能脉冲通过两根光纤的传输，远高于在非接触和接触模式下消融生物组织所需的阈值。经过10m的HC-NCF和>；3400J/cm2的HC-PCF，传输的能量密度达到>；750J/cm-2。
In this work we present the delivery of high energy Er:YAG laser pulses operating at 2.94 μm through a hollow-core negative curvature fibre (HC-NCF) and a hollow-core photonic crystal fibre (HC-PCF) and their use for the ablation of biological tissue. In HC-NCF fibres, which have been developed recently, the laser radiation is confined in a hollow core and by an anti-resonant or reflection principle (also known as ARROW). Both fibres are made of fused silica which has high mechanical and chemical durability, is bio-inert and results in a fibre with the flexibility that lends itself to easy handling and minimally invasive procedures. The HC-NCF structure consists of only one ring of capillaries around a realtively large core, followed by a protecting outer layer, hence the preform is relatively easy to build compared to traditional HC-PCF. The measured attenuation at 2.94 μm is 0.06 dB/m for the HC-NCF and 1.2 dB/m for the HC-PCF. Both fibres have a single mode output beam profile which can be advantageous for surgical applications as the beam profile is maintained during fibre movement. We demonstrate delivery of high energy pulses through both fibres, well above the thresholds needed for the ablation of biological tissue in non-contact and contact mode. Delivered energy densities reached > 750 J/cm-2after 10 m of HC-NCF and > 3400 J/cm2through a 44 cm HC-PCF.