A peritrophin-like protein expressed in the embryonic tracheae of Drosophila melanogaster
A peritrophin-like protein expressed in the embryonic tracheae of Drosophila melanogaster
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DOI：
10.1016/s0965-1748(99)00004-1
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发表时间：
1999-04-01
影响因子：
3.8
通讯作者：
Christensen, AC
中科院分区：
文献类型：
--
作者：
Barry, MK;Triplett, AA;Christensen, AC
我们已经克隆和测序的cDNA从果蝇，编码一个蛋白质同源的peritrophins，一个家庭的几丁质结合蛋白从围食基质的昆虫。出乎意料的是，基因Gasp在胚胎气管中表达。我们认为，这个家族的蛋白质可能存在于其他组织比围食基质，特别是在营养或气体交换是重要的，和/或寄生虫或病毒的入侵是可能的。我们还绘制了伯克利果蝇基因组计划测序的两个相似基因的图谱，发现这三个非常相似的基因并没有聚集在一起，而是位于三条不同的染色体上。(C)1999爱思唯尔科技有限公司。保留所有权利。
We have cloned and sequenced a cDNA from Drosophila melanogaster that encodes a protein homologous to the peritrophins, a family of chitin-binding proteins from the peritrophic matrix of insects. Unexpectedly, the gene, Gasp, is expressed in the embryonic tracheae. We suggest that this family of proteins may be present in other tissues than the peritrophic matrix, particularly where nutrient or gas exchange are important, and/or where invasion by parasites or viruses is possible. We have also mapped two similar genes that had been sequenced by the Berkeley Drosophila Genome project, and find that these three very similar genes are not clustered, but are located on three different chromosomes. (C) 1999 Elsevier Science Ltd. All rights reserved.