Functional characterization of OXA-57, a class D β-lactamase from Burkholderia pseudomallei
Functional characterization of OXA-57, a class D β-lactamase from Burkholderia pseudomallei
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DOI：
10.1128/aac.49.4.1639-1641.2005
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发表时间：
2005-04-01
影响因子：
4.9
通讯作者：
Brown, KA
中科院分区：
文献类型：
--
作者：
Keith, KE;Oyston, PC;Brown, KA
Class D beta-lactamase OXA-57 was identified in a range of isolates of Burkholderia pseudomallei and Burkholderia thailandensis. Comparative kinetic analyses of wild-type and mutant forms of B. pseudomallei OXA-57 are reported. Implications of these data for beta-lactam resistance and the proposed role of Ser-104 in beta-lactam hydrolysis are discussed.
