Genome-wide approaches to identifying genetic factors in host susceptibility to tuberculosis
Genome-wide approaches to identifying genetic factors in host susceptibility to tuberculosis
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DOI：
10.1016/j.micinf.2005.10.025
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发表时间：
2006-04-01
影响因子：
5.8
通讯作者：
Bellamy, Richard
中科院分区：
文献类型：
--
作者：
Bellamy, Richard
宿主遗传因素在决定对结核分枝杆菌的易感性方面是重要的。在人类和结核病易感性小鼠模型中进行了全基因组连锁研究。这些研究已经确定了几个重要的结核病易感性候选基因座。这是解决该疾病复杂病因的重要一步。(c)2006年爱思唯尔SAS。All rights reserved.
Host genetic factors are important in determining susceptibility to Mycobacterium tuberculosis. Genome-wide linkage studies have been performed in humans and in murine models of tuberculosis susceptibility. These studies have identified several important candidate loci for susceptibility to tuberculosis. This is an important step in resolving the complex etiology of the disease. (c) 2006 Elsevier SAS. All rights reserved.