2 NEW RATING-SCALES FOR OPIATE WITHDRAWAL
2 NEW RATING-SCALES FOR OPIATE WITHDRAWAL
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DOI：
10.3109/00952998709001515
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发表时间：
1987-01-01
影响因子：
2.7
通讯作者：
KANOF, PD
中科院分区：
文献类型：
--
作者：
HANDELSMAN, L;COCHRANE, KJ;KANOF, PD
两个新的评级量表测量阿片类药物戒断的体征和症状。主观阿片类戒断量表（SOWS）包含16种症状，其强度由患者在0（完全没有）至4（极度）的量表上评定。客观阿片类戒断量表（OOWS）包含13个身体上可观察到的体征，根据评定者对患者的定时观察，评定为存在或不存在。戒毒病房的阿片类药物滥用者接受美沙酮治疗前的SOWS和OOWS评分显著高于接受美沙酮治疗2天后。寻求治疗的阿片类药物滥用者接受安慰剂或0.4 mg纳洛酮治疗。纳洛酮组的激发后SOWS和OOWS评分显着高于激发前评分，但安慰剂组则不然。我们已经证明了良好的评价者间的可靠性OOWS和良好的受试者内的可靠性随着时间的推移，这两个规模的控制和美沙酮维持治疗计划的患者。这些量表被证明是有效和可靠的指标阿片类药物戒断综合征的严重程度在广泛的常见体征和症状。
Two new rating scales for measuring the signs and symptoms of opiate withdrawal are presented. The Subjective Opiate Withdrawal Scale (SOWS) contains 16 symptoms whose intensity the patient rates on a scale of 0 (not at all) to 4 (extremely). The Objective Opiate Withdrawal Scale (OOWS) contains 13 physically observable signs, rated present or absent, based on a timed period of observation of the patient by a rater. Opiate abusers admitted to a detoxification ward had significantly higher scores on the SOWS and OOWS before recieving methadone as compared to after receiving methadone for 2 days. Opiate abusers seeking treatment were challenged either with placebo or with 0.4 mg naloxone. Postchallenge SOWS and OOWS scores were significantly higher than prechallenge scores in the naloxone but not the placebo group. We have demonstrated good interrater reliability for the OOWS and good intrasubject reliability over time for both scales in controls and in patients on a methadone maintenance program. These scales are demonstrated to be valid and reliable indicators of the severity of the opiate withdrawal syndrome over a wide range of common signs and symptoms.