A MILD SINGLE-STEP REDUCTION OF OXIMES TO AMINES
A MILD SINGLE-STEP REDUCTION OF OXIMES TO AMINES
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DOI：
10.1080/00397918808057845
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发表时间：
1988-01-01
影响因子：
2.1
通讯作者：
KIRST, HA
中科院分区：
文献类型：
--
作者：
LEEDS, JP;KIRST, HA
已经开发出一种温和且方便的方法，用于在一步中将肟还原为胺，包括在 NaBH3CN 存在下用 TiCl3 处理肟。该方法对于中间体亚胺容易水解的那些底物特别有用。
A mild and convenient procedure has been developed for the reduction of oximes to amines in a single step involving treatment of the oxime with TiCl3in the presence of NaBH3CN. This method is especially useful for those substrates in which the intermediate imine is readily hydrolyzed.