CONFIDENTIAL HIV TESTING AND CONDOM PROMOTION IN AFRICA - IMPACT ON HIV AND GONORRHEA RATES
CONFIDENTIAL HIV TESTING AND CONDOM PROMOTION IN AFRICA - IMPACT ON HIV AND GONORRHEA RATES
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DOI：
10.1001/jama.268.23.3338
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发表时间：
1992-12-16
影响因子：
120.7
通讯作者：
HULLEY, S
中科院分区：
文献类型：
--
作者：
ALLEN, S;SERUFILIRA, A;HULLEY, S
目标。我们评估了人类免疫缺陷病毒（HIV）检测和咨询对卢旺达城市妇女自我报告的避孕套和杀精剂使用情况以及相应的HIV血清转化和淋病率的影响。-前瞻性队列研究，随访2年，比较干预前后的结果变量，以及未接受干预的对照组的安全套使用情况。-卢旺达首都基加利的门诊研究诊所。- 1988年，1458名育龄妇女（其中32%感染了艾滋病毒）参加了一项前瞻性研究，每隔3至6个月随访2年。95%的受试者在第一年和92%的受试者在第二年进行了随访。-向所有参与者和感兴趣的性伴侣提供了获得性免疫缺陷综合症（艾滋病）教育录像带、艾滋病毒检测和咨询、免费避孕套和杀精剂。主要结果测量。-自我报告避孕套-杀精剂使用依从性及观察到的HIV和淋病发病率。-只有7%的妇女报告在干预前使用过避孕套，但22%的妇女报告一年后使用避孕套的依从性良好。感染艾滋病毒的妇女比感染艾滋病毒的妇女更有可能使用避孕套(36%对16%；P
Objective.-We evaluated the impact of human immunodeficiency virus (HIV) testing and counseling on self-reported condom and spermicide use and on corresponding HIV seroconversion and gonorrhea rates in urban Rwandan women.Design.-Prospective cohort study with 2 years of follow-up, comparison of outcome variables before and after an intervention, and condom use measured in a control group that did not receive the intervention.Setting.-Outpatient research clinic in Kigali, the capital of Rwanda.Participants.-One thousand four hundred fifty-eight childbearing women, 32% of whom were infected with HIV, were enrolled in a prospective study in 1988, and followed at 3- to 6-month intervals for 2 years. Follow-up was available for 95% of subjects at year 1 and 92% at year 2.Interventions.-An acquired immunodeficiency syndrome (AIDS) educational videotape, HIV testing and counseling, and free condoms and spermicide were provided to all participants and interested sexual partners.Main Outcome Measures.-Self-report of compliance with condom-spermicide use and observed incidence of HIV and gonorrhea.Results.-Only 7% of the women reported ever trying condoms before the intervention, but 22% reported condom use with good compliance 1 year later. Women who were HIV-positive were more likely to adopt condom use than HIV-negative women (36% vs 16%; P