Syphilis surveillance and trends of the syphilis epidemic in Germany since the mid-90s.
Syphilis surveillance and trends of the syphilis epidemic in Germany since the mid-90s.
复制标题
DOI：
10.2807/esm.09.12.00494-en
复制
发表时间：
2004-12-01
期刊：
影响因子：
--
通讯作者：
Hamouda, O
中科院分区：
文献类型：
--
作者：
Marcus, U;Bremer, V;Hamouda, O
欧洲和美国最近的监测报告显示梅毒病例有所增加。关于梅毒分布的准确流行病学信息对于有针对性的筛查和干预方案非常重要。2001年，德国的梅毒报告制度从医生报告改为实验室报告，并辅之以新采用的性传播感染哨点制度。在1990年代达到历史最低点后，梅毒报告自2001年以来显著增加，与新报告制度的引入相吻合。然而，报告发病率的增加反映了病例数的真实增加，而不是主要由以前报告制度中的更多漏报决定的。这一增长反映了男男性行为者（MSM）中的梅毒爆发。1997年在汉堡观察到第一次暴发。2003年，男性的发病率比女性高10倍。据估计，目前75%的梅毒病例是在男男性行为者中诊断出来的。在被诊断患有梅毒的男男性行为者中，艾滋病毒呈阳性的比例很高（根据哨点数据，高达50%）。与其他西欧国家相比，近年来德国异性恋者中确诊的梅毒病例数持续较高，这可能反映了德国与东南欧和东欧梅毒高发区之间较高的人口流动。关于梅毒分布的准确流行病学信息对于有针对性的筛查和干预方案非常重要。2001年，德国的梅毒报告制度从医生报告改为实验室报告，并辅之以新采用的性传播感染哨点制度。在1990年代达到历史最低点后，梅毒报告自2001年以来显著增加，与新报告制度的引入相吻合。然而，报告发病率的增加反映了病例数的真实增加，而不是主要由以前报告制度中的更多漏报决定的。这一增长反映了男男性行为者（MSM）中的梅毒爆发。1997年在汉堡观察到第一次暴发。2003年，男性的发病率比女性高10倍。据估计，目前75%的梅毒病例是在男男性行为者中诊断出来的。在被诊断患有梅毒的男男性行为者中，艾滋病毒呈阳性的比例很高（根据哨点数据，高达50%）。与其他西欧国家相比，近年来德国异性恋者中诊断出的梅毒病例数持续较高，这可能反映了德国与东南欧和东欧梅毒高发区之间较高的人口流动。
Recent surveillance reports from Europe and the United States show an increase in syphilis cases. Accurate epidemiological information about the distribution of syphilis is important for targeting screening and intervention programmes. The German syphilis notification system changed in 2001 from physician to laboratory-based reporting, which is complemented by a newly introduced sexually transmitted infection (STI) sentinel system. After reaching an all time low during the 1990s, syphilis notifications have increased significantly since 2001, coinciding with the introduction of the new reporting system. However, the increased reported incidence is reflecting a true rise in the number of cases and is not predominantly determined by more underreporting through the previous reporting system. The increase reflects syphilis outbreaks among men who have sex with men (MSM). The first of these outbreaks was observed in Hamburg in 1997. In 2003, incidence in men was ten times higher than in women. An estimated 75% of syphilis cases are currently diagnosed among MSM. A high proportion (according to sentinel data, up to 50%) of MSM diagnosed with syphilis are HIV positive. The continuously high number of syphilis cases diagnosed among heterosexuals in Germany in recent years compared with other western European countries may reflect the higher population movement between Germany and syphilis high incidence regions in south-east and eastern Europe.Recent surveillance reports from Europe and the United States show an increase in syphilis cases. Accurate epidemiological information about the distribution of syphilis is important for targeting screening and intervention programmes. The German syphilis notification system changed in 2001 from physician to laboratory-based reporting, which is complemented by a newly introduced sexually transmitted infection (STI) sentinel system. After reaching an all time low during the 1990s, syphilis notifications have increased significantly since 2001, coinciding with the introduction of the new reporting system. However, the increased reported incidence is reflecting a true rise in the number of cases and is not predominantly determined by more underreporting through the previous reporting system. The increase reflects syphilis outbreaks among men who have sex with men (MSM). The first of these outbreaks was observed in Hamburg in 1997. In 2003, incidence in men was ten times higher than in women. An estimated 75% of syphilis cases are currently diagnosed among MSM. A high proportion (according to sentinel data, up to 50%) of MSM diagnosed with syphilis are HIV positive. The continuously high number of syphilis cases diagnosed among heterosexuals in Germany in recent years compared with other western European countries may reflect the higher population movement between Germany and syphilis high incidence regions in south-east and eastern Europe.