Inserted sequences in bovine satellite DNA's.

Inserted sequences in bovine satellite DNA's.
复制标题

将序列插入牛卫星 DNA 中。

DOI:
10.1126/science.6264600
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发表时间:
1981
期刊:
影响因子:
56.9
通讯作者:
R. Streeck
R. Streeck
中科院分区:
综合性期刊1区
文献类型:
--
作者:
R. Streeck

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测定了牛1.711a卫星DNA1413碱基对重复单位的核苷酸序列(氯化铯密度,1.711克/立方厘米)。重复单位包含两个片段,由基本23碱基对序列的变体组成,该序列与牛1.706卫星DNA序列密切相关。重复单元的第三个片段包含不相关的611碱基对序列,该序列不是内部重复的。该片段两侧是8个碱基对的反向重复,一侧是末端序列的直接重复。牛1.711b卫星DNA中存在一个相关片段,并被插入到来自1.715卫星的序列中。这些核苷酸序列表明了这些复杂的、密切相关的卫星DNA进化的某些阶段的时间,并表明了它们与共同祖先背道而驰的内在机制。
The nucleotide sequence of the 1413-base-pair repeat unit of bovine 1.711a satellite DNA (density in cesium chloride, 1.711 grams per cubic centimeter) has been determined. The repeat unit contains two segments consisting of variants of a basic 23-base-pair sequence that is closely related to sequences of bovine 1.706 satellite DNA. A third segment of the repeat unit contains an unrelated 611-base-pair sequence that is not internally repetitive. This segment is flanked by inverted repeats of 8 base pairs and, on one side, by a direct repeat of the terminal sequence. A related segment is present in bovine 1.711b satellite DNA and is inserted into sequences derived from the 1.715 satellite. These nucleotide sequences suggest the timing of some of the stages in the evolution of these complex, closely related satellite DNA's and indicate the mechanisms inherent in their divergence from a common ancestor.