Accuracy of generic musculoskeletal models in predicting the functional roles of muscles in human gait
Accuracy of generic musculoskeletal models in predicting the functional roles of muscles in human gait
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DOI：
10.1016/j.jbiomech.2011.05.023
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发表时间：
2011-07-28
影响因子：
2.4
通讯作者：
Pandy, Marcus G.
中科院分区：
文献类型：
--
作者：
Correa, Tomas A.;Baker, Richard;Pandy, Marcus G.
肌肉功能的生物力学评估通常使用从尸体上获得的解剖测量数据创建的通用肌肉骨骼模型进行。理解使用通用模型来研究运动生物力学的有效性是至关重要的，特别是当这些模型被应用于分析行动障碍者的行走模式时。本研究的目的是评估比例通用模型在确定步态中下肢肌肉的力臂和功能角色方面的准确性。肌肉的功能作用是通过其促进关节加速或整个身体重心加速的潜力来描述的。肌肉的潜在加速度被定义为由一个单位的肌肉力引起的加速度。对四名脑瘫儿童和五名年龄匹配的对照组进行了动态模拟。每个受试者由一个按比例划分的通用模型和一个由磁共振（MR）成像建立的模型来表示。根据每个受试者的比例通用模型得出的计算结果与相应的基于核磁共振的模型得出的计算结果进行评估。使用这两种模型计算的肌肉力臂存在显著差异。这些差异扩展到肌肉潜在加速度的计算，但肌肉功能的预测（即肌肉加速关节或质心的方向以及肌肉相对于其他肌肉的潜在加速度的大小）在两种建模技术之间是一致的。我们的研究结果表明，比例通用模型和基于图像的模型在正常和病理步态中产生相似的肌肉功能评估。(c) 2011 Elsevier Ltd.版权所有。
Biomechanical assessments of muscle function are often performed using a generic musculoskeletal model created from anatomical measurements obtained from cadavers. Understanding the validity of using generic models to study movement biomechanics is critical, especially when such models are applied to analyze the walking patterns of persons with impaired mobility. The aim of this study was to evaluate the accuracy of scaled-generic models in determining the moment arms and functional roles of the lower-limb muscles during gait. The functional role of a muscle was described by its potential to contribute to the acceleration of a joint or the acceleration of the whole-body center of mass. A muscle's potential acceleration was defined as the acceleration induced by a unit of muscle force. Dynamic simulations of walking were generated for four children with cerebral palsy and five age-matched controls. Each subject was represented by a scaled-generic model and a model developed from magnetic resonance (MR) imaging. Calculations obtained from the scaled-generic model of each subject were evaluated against those derived from the corresponding MR-based model. Substantial differences were found in the muscle moment arms computed using the two models. These differences propagated to calculations of muscle potential accelerations, but predictions of muscle function (i.e., the direction in which a muscle accelerated a joint or the center of mass and the magnitude of the muscle's potential acceleration relative to that of other muscles) were consistent between the two modeling techniques. Our findings suggest that scaled-generic models and image-based models yield similar assessments of muscle function in both normal and pathological gait. (c) 2011 Elsevier Ltd. All rights reserved.