Psychosocial and demographic factors influencing pain scores of patients with knee osteoarthritis.
Psychosocial and demographic factors influencing pain scores of patients with knee osteoarthritis.
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DOI：
10.1371/journal.pone.0195075
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Schenck R
中科院分区：
文献类型：
--
作者：
Eberly L;Richter D;Comerci G;Ocksrider J;Mercer D;Mlady G;Wascher D;Schenck R
膝关节骨关节炎（OA）患者的疼痛水平通常通过使用数字评分系统进行评估，但结果可能受到患者实际身体不适或疾病严重程度以外的因素的影响，包括社会心理和人口统计学变量。我们在355例膝关节炎患者中研究了膝关节疼痛评分与一些社会心理、社会人口学、疾病和治疗变量之间的可能关系。疼痛评估工具是一个0到10分的评分量表。从患者病历中回顾性获得的数据包括人口统计学特征、体重指数（BMI）、伴随疾病、非法和处方药物使用、酒精使用、吸烟、膝关节OA治疗以及膝关节OA的严重程度（Kellgren-Lawrence （KL）放射分级）。进行单变量和多变量分析以确定这些变量是否与报告的疼痛评分相关。在单变量分析中，较高的疼痛评分与美洲原住民或西班牙裔显著相关；较高的身体质量指数；目前阿片类药物、抗抑郁药或加巴喷丁类药物的处方；抑郁症;糖尿病;纤维肌痛;非法使用药物；缺乏医疗保险；吸烟;既往膝关节注射；临床医生建议患者进行膝关节手术。患者的性别和KL分级均无相关性。在多变量分析中，抑郁症、当前阿片类药物处方、美洲原住民或西班牙裔种族与较高的疼痛评分保持显著关联。我们在一个大的、种族多样化的膝关节OA患者群体中的研究结果表明，社会心理和社会人口因素可能是膝关节OA患者报告的疼痛程度的重要决定因素。
Pain levels in patients with osteoarthritis (OA) of the knee are commonly assessed by using a numeric scoring system, but results may be influenced by factors other than the patient’s actual physical discomfort or disease severity, including psychosocial and demographic variables. We examined the possible relation between knee-pain scores and several psychosocial, sociodemographic, disease, and treatment variables in 355 patients with knee OA. The pain-evaluation instrument was a 0- to 10-point rating scale. Data obtained retrospectively from the patients’ medical records were demographic characteristics, body mass index (BMI), concomitant disorders, illicit and prescription drug use, alcohol use, smoking, knee OA treatment, and severity of knee OA indicated by Kellgren-Lawrence (KL) radiographic grade. Univariate and multivariate analyses were performed to determine whether these variables correlated with reported pain scores. On univariate analysis, higher pain scores were significantly associated with Native American or Hispanic ethnicity; a higher BMI; current prescription for an opioid, antidepressant, or gabapentinoid medication; depression; diabetes mellitus; fibromyalgia; illicit drug use; lack of health insurance; smoking; previous knee injection; and recommendation by the clinician that the patient undergo knee surgery. Neither the patient’s sex nor the KL grade showed a correlation. On multivariate analysis, depression, current opioid prescription, and Native American or Hispanic ethnicity retained a significant association with higher pain scores. Our results in a large, ethnically diverse group of patients with knee OA suggest that psychosocial and sociodemographic factors may be important determinants of pain levels reported by patients with knee OA.
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影响因子：
4.7
作者：
Somers, Tamara J.;Keefe, Francis J.;Pells, Jennifer J.;Dixon, Kim E.;Waters, Sandra J.;Riordan, Paul A.;Blumenthal, James A.;Mckee, Daphne C.;LaCaille, Lara;Tucker, Jessica N.;Schmitt, Daniel;Caldwell, David S.;Kraus, Virginia B.;Sims, Ershela L.;Shelby, Rebecca A.;Rice, John R.
通讯作者：
Rice, John R.
影响因子：
--
作者：
Lawrence, Reva C.;Felson, David T.;Wolfe, Frederick
通讯作者：
Wolfe, Frederick
影响因子：
4.7
作者：
Castrejon, Isabel;Yazici, Yusuf;Pincus, Theodore
通讯作者：
Pincus, Theodore
影响因子：
4.2
作者：
Pud, D;Cohen, D;Eisenberg, E
通讯作者：
Eisenberg, E
影响因子：
--
作者：
SUMMERS, MN;HALEY, WE;ALARCON, GS
通讯作者：
ALARCON, GS