THE MEMORIAL SYMPTOM ASSESSMENT SCALE - AN INSTRUMENT FOR THE EVALUATION OF SYMPTOM PREVALENCE, CHARACTERISTICS AND DISTRESS
THE MEMORIAL SYMPTOM ASSESSMENT SCALE - AN INSTRUMENT FOR THE EVALUATION OF SYMPTOM PREVALENCE, CHARACTERISTICS AND DISTRESS
复制标题
DOI：
10.1016/0959-8049(94)90182-1
复制
发表时间：
1994-01-01
影响因子：
8.4
通讯作者：
SCHER, H
中科院分区：
文献类型：
--
作者：
PORTENOY, RK;THALER, HT;SCHER, H
memorial症状评估量表（MSAS）是一种新的由患者评定的工具，其开发目的是提供关于多种常见症状的多维信息。本研究评估了MSAS在癌症人群中的信度和效度。使用MSAS以及一系列独立评估与生活质量相关现象的测量方法，对随机选取的前列腺癌、结肠癌、乳腺癌或卵巢癌的住院患者和门诊患者（n = 246）进行了评估。在218名可评估患者中，症状发生率从缺乏精力的73.9%到吞咽困难的10.6%不等。基于内容分析，删除了3种症状并增加了2种；修订后的量表评估32种身体和心理症状。方差因子分析得出两个因子，区分了三个主要症状组和几个亚组。主要组包括心理症状（PSYCH）、高发生率身体症状（PHYS H）和低发生率身体症状（PHYS L）。PHYS H和PSYCH组的内部一致性较高（克朗巴赫α系数分别为0.88和0.83），PHYS L组的内部一致性适中（α = 0.58）。尽管严重程度、频率和痛苦程度维度高度相关，但典型相关和其他分析表明，多维评估（频率和痛苦程度）增加了关于症状影响的信息。与临床状况和生活质量测量的高度相关性支持了MSAS的效度，并表明了几个分量表分数的效用，包括PSYCH、PHYS和一个简短的总体痛苦指数。MSAS是一种用于评估症状发生率、特征和痛苦程度的可靠且有效的工具。它提供了一种全面的症状评估方法，当需要症状信息时可能很有用，例如纳入生活质量测量的临床试验或症状流行病学研究。
The Memorial Symptom Assessment Scale (MSAS) is a new patient-rated instrument that was developed to provide multidimensional information about a diverse group of common symptoms. This study evaluated the reliability and validity of the MSAS in the cancer population. Randomly selected inpatients and outpatients (n=246) with prostate, colon, breast or ovarian cancer were assessed using the MSAS and a battery of measures that independently evaluate phenomena related to quality of life. Symptom prevalence in the 218 evaluable patients ranged from 73.9% for lack of energy to 10.6% for difficulty swallowing. Based on a content analysis, three symptoms were deleted and two were added; the revised scale evaluates 32 physical and psychological symptoms. A factor analysis of variance yielded two factors that distinguished three major symptom groups and several subgroups. The major groups comprised psychological symptoms (PSYCH), high prevalence physical symptoms (PHYS H), and low prevalence (PHYS L). Internal consistency was high in the PHYS H and PSYCH groups (Cronback alpha coefficients of 0.88 and 0.83, respectively), and moderate in the PHYS L group (alpha = 0.58). Although the severity, frequency and distress dimensions were highly intercorrelated, canonical correlations and other analyses demonstrated that multidimensional assessment (frequency and distress) augments information about the impact of the symptoms. High correlations with clinical status and quality of life measures support the validity of the MSAS and indicate the utility of several subscale scores, including PSYCH, PHYS, and a brief Global Distress Index. The MSAS is a reliable and valid instrument for the assessment of symptom prevalence, characteristics and distress. It provides a method for comprehensive symptom assessment that may be useful when information about symptoms is desirable, such as clinical trials that incorporate quality of life measures or studies of symptom epidemiology.