Selective retina therapy (SRT) for macular serous retinal detachment associated with tilted disc syndrome
Selective retina therapy (SRT) for macular serous retinal detachment associated with tilted disc syndrome
复制标题
选择性视网膜治疗（SRT）治疗与倾斜椎间盘综合征相关的黄斑浆液性视网膜脱离
DOI：
10.1007/s00417-020-04931-1
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Honda Shigeru
中科院分区：
文献类型：
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作者：
Hirayama Kumiko;Yamamoto Manabu;Kohno Takeya;Kyo Akika;Theisen-Kunde Dirk;Brinkmann Ralf;Miura Yoko;Honda Shigeru
目的倾斜视盘综合征(TDS)可能与黄斑浆液性视网膜脱离(MSRD)相关。然而，对于这种并发症的理想治疗方法至今仍未确定。目的探讨选择性视网膜治疗(SRT)治疗MSRD合并TDS的疗效。方法对10例(11只眼)MSRD合并TDS患者行选择性视网膜治疗(SRT)，观察治疗后至少12个月的疗效。平均年龄56岁(44~66岁)。采用同步辐射激光治疗(波长5 2 7 nm，1 7μS，10 0赫兹，德国L医学激光中心)。观察最佳矫正视力(BCVA)、中央黄斑厚度(CMT)、中央脉络膜厚度(CCT)的变化。结果随访12~48个月，平均24.4个月。平均斜视视力由术前的0.03±0.10、324±82μm、194±68μm恢复到术后的0.07±0.17、274±94μm、188±65μm，差异有统计学意义(P=0.44、0.05、P=0.21)。6只眼(55%)MSRD消失，平均照射次数达到MSRD的2.6倍(范围1~5倍)。SFCH与MSRD的消退无显著相关性(p=0.19)。结论SRT可促进MSRD的吸收，维持TDS患者的BCVA。需要随机和前瞻性的临床研究来评估SRT治疗MSRD合并TDS的有效性。
PurposeTilted disc syndrome (TDS) may be associated with a macular serous retinal detachment (MSRD). However, ideal therapy for this complication is still unestablished yet to date. The purpose of this study is to investigate the effect of selective retina therapy (SRT) for MSRD associated with TDS.MethodsThis retrospective study included 11 eyes of 10 patients (1 male and 9 females), who were treated with SRT for MSRD associated with TDS, and observed at least 12 months after treatment. The mean age was 56 years old (range 44–66). An SRT laser (527 nm, 1.7 μs, 100 Hz; Medical Laser Center Lübeck, Germany) was used for treatment. The changes of best-corrected visual acuity (BCVA), central macular thickness (CMT), and central choroidal thickness (CCT) were examined. Subfoveal curve height (SFCH) was calculated at baseline.ResultsThe mean follow-up period was 24.4 months (range 12–48 months). The mean BCVA (logMAR), CMT, and CCT changed from 0.03 ± 0.10, 324 ± 82 μm, and 194 ± 68 μm preoperatively to 0.07 ± 0.17, 274 ± 94 μm, and 188 ± 65 μm at final follow-up, respectively, with significant difference on CMT (BCVA:p= 0.44, CMT:p< 0.05, CCT:p= 0.21). The MSRD disappeared in 6 eyes (55%) and the average number of SRT irradiations until resolution of MSRD was 2.6 times (range 1–5 times). There was no significant association between SFCH and resolution of MSRD (p= 0.19).ConclusionsSRT may promote absorption of MSRD and maintenance of BCVA for TDS. Randomized and prospective clinical studies are needed to evaluate the effectiveness of SRT for MSRD associated with TDS.