Improvement in mental depression with decreased thyrotropin response after administration of thyrotropin-releasing hormone.
Improvement in mental depression with decreased thyrotropin response after administration of thyrotropin-releasing hormone.
复制标题
服用促甲状腺激素释放激素后，由于促甲状腺激素反应降低，精神抑郁得到改善。
DOI：
10.1016/s0140-6736(72)92028-4
复制
发表时间：
1972
期刊：
影响因子：
168.9
通讯作者：
M. Anderson
中科院分区：
文献类型：
--
作者：
A. Kastin;R. Ehrensing;D. Schalch;M. Anderson
5例精神抑郁症患者接受促甲状腺激素（T.S.H.）治疗，释放激素作为双盲交叉研究的一部分。所有患者的抑郁症状均有所改善。血浆-促甲状腺激素。对T.R.H.的回应5例患者中有4例明显减少，提示下丘脑/垂体轴异常。
Five patients with mental depression received thyrotropin (T.S.H.)-releasing hormone (T.R.H.) for 3 days as part of a double-blind, cross-over study. All patients showed improvement in the symptoms of depression. The plasma-T.S.H. response to T.R.H. was distinctly diminished in four of the five patients, suggesting an abnormality in the hypothalamic/pituitary axis.