Problems in determining occurrence rates of multimorbidity
Problems in determining occurrence rates of multimorbidity
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DOI：
10.1016/s0895-4356(00)00358-9
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发表时间：
2001-07-01
影响因子：
7.2
通讯作者：
Knottnerus, JA
中科院分区：
文献类型：
--
作者：
van den Akker, M;Buntinx, F;Knottnerus, JA
本文介绍了在研究多种病理学时必须做出的方法学决定，并提出了适当的分析技术。这篇文章的主要问题是：如何可以合并症和多合并症的操作方面的疾病的数量和类型的研究。哪些分析方法可用于多种病理学的评估？研究疾病的数量和类型的选择对观察到的合并症和多合并症的发病率和患病率有很大影响。这些比率在很大程度上取决于年龄。性和其他决定因素。除了粗略的描述性测量外，比值比和相对风险也可用于研究合并症。而可以使用观测/预期比率来研究多变量。虽然可以使用标准统计软件包进行合并症的基本分析，但开发了两个额外的程序，分别用于分析多合并症和统计学上意外的合并症的分布。由于一些分析涉及多重比较，建议进行外部有效性测试。(C)2001 Elsevier Science Inc. All rights reserved.
This article describes methodological decisions that have to be made when studying multiple pathology and presents appropriate analytical techniques. The main question of this article is: how can comorbidity and multimorbidity be operationalized with respect to the number and type of diseases studied. and which analytic approaches are available for the evaluation of multiple pathology? Choices regarding the number and type of diseases studied have great impact on the observed incidence and prevalence rates of comorbidity and multimorbidity. These rates are largely dependent on age. sex, and other determinants. In addition to crude descriptive measures, odds ratios and relative risks can be used to study comorbidity. whereas multimorbidity can be studied using observed/expected ratios. While basic analyses of comorbidity can be performed using standard statistical packages, two additional programs were developed for the analysis of the distribution of multimorbidity and statistically unexpected comorbidity, respectively. As some analyses are addressing multi-comparisons, external validity testing is recommended. (C) 2001 Elsevier Science Inc. All rights reserved.