Multiorgan, Multimodality Imaging in Cardiometabolic Disease.
Multiorgan, Multimodality Imaging in Cardiometabolic Disease.
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DOI：
10.1161/circimaging.117.005447
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发表时间：
2017-11
期刊：
影响因子：
--
通讯作者：
Raman SV
中科院分区：
文献类型：
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作者：
Kumar V;Hsueh WA;Raman SV
心脏代谢疾病，包括肥胖症到2型糖尿病等具有过度心血管风险的疾病，是一个主要的公共卫生负担。临床前转化科学的进展指出了多器官系统的潜在靶点，以进行早期干预，改善心脏代谢健康。临床试验的验证和转化为护理将受益于促进治疗进步的体内诊断技术。这篇综述提供了一个最先进的，多模态的观点，跨越多个器官系统（图），有助于心脏代谢疾病。
Cardiometabolic disease, spanning conditions such as obesity to type 2 diabetes mellitus with excess cardiovascular risk, represents a major public health burden. Advances in preclinical translational science point to potential targets across multiple organ systems for early intervention to improve cardiometabolic health. Validation in clinical trials and translation to care would benefit from in vivo diagnostic techniques that facilitate therapeutic advancements. This review provides a state-of-the-art, multi-modality perspective spanning the multiple organ systems (Figure) that contribute to cardiometabolic disease.