Effects of Chemical Cross-linkers on Caries-affected Dentin Bonding
Effects of Chemical Cross-linkers on Caries-affected Dentin Bonding
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DOI：
10.1177/0022034509351001
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发表时间：
2009-12-01
影响因子：
7.6
通讯作者：
Bedran-Russo, A. K.
中科院分区：
文献类型：
--
作者：
Macedo, G. V.;Yamauchi, M.;Bedran-Russo, A. K.
如何使复合树脂与牙本质之间形成牢固、稳定的粘结，一直是口腔修复领域的一个难题。在过去的二十年里，牙科材料得到了很大的改进，具有更好的处理和粘合特性。然而，很少有人关注胶原结构/稳定性对粘合强度的贡献。我们假设，诱导牙本质胶原交联提高牙本质胶原的稳定性和粘结强度。本研究探讨了戊二醛和葡萄籽提取物诱导的交联对健康和龋损牙本质的牙本质粘结强度以及牙本质胶原稳定性的影响。我们的研究结果表明，化学交联剂的应用程序，以蚀刻牙本质粘结程序之前显着增强的牙本质粘结强度的龋影响和健全的牙本质。戊二醛和葡萄籽提取物显着增加牙本质胶原蛋白的稳定性，在健全和龋齿影响的牙本质，可能通过不同的机制。
The achievement of a strong and stable bond between composite resin and dentin remains a challenge in restorative dentistry. Over the past two decades, dental materials have been substantially improved, with better handling and bonding characteristics. However, little attention has been paid to the contribution of collagen structure/stability to bond strength. We hypothesized that the induction of cross-linking in dentin collagen improves dentin collagen stability and bond strength. This study investigated the effects of glutaraldehyde- and grape seed extract-induced cross-linking on the dentin bond strengths of sound and caries-affected dentin, and on the stability of dentin collagen. Our results demonstrated that the application of chemical cross-linking agents to etched dentin prior to bonding procedures significantly enhanced the dentin bond strengths of caries-affected and sound dentin. Glutaraldehyde and grape seed extract significantly increased dentin collagen stability in sound and caries-affected dentin, likely via distinct mechanisms.