Acute leukemia association with psoriasis: A report on 100 patients from a single center in China
Acute leukemia association with psoriasis: A report on 100 patients from a single center in China
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急性白血病与银屑病的关联：来自中国单个中心的 100 名患者的报告
DOI：
10.1002/ajh.21683
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发表时间：
2010-05
影响因子：
12.8
通讯作者：
Wang, Jianxiang
中科院分区：
文献类型：
--
作者：
Wang, Ying;Mi, Yingchang;Li, Dapeng;Xue, Yanping;Bian, Shougeng;Wang, Jianxiang
牛皮癣和白血病之间的关系是一个有争议的话题。100例急性白血病（AL）银屑病患者根据银屑病治疗分为三组：（i）乙双吗啉治疗组（n = 35）;（ii）非乙双吗啉治疗组（n = 45）;（iii）未治疗组（n = 20）。最常见的与银屑病相关的白血病类型是急性早幼粒细胞白血病（APL）。乙双吗啉治疗组非复发性克隆性染色体结构畸变比例（42.9%）显著高于非乙双吗啉治疗组（17.1%）和未治疗组（21.4%）（P < 0.05）。在非APL患者中，非乙双吗啉治疗组第一疗程完全缓解率（84.2%）明显高于乙双吗啉治疗组（8.3%）和未治疗组（37.5%）（P < 0.05）。乙双吗啉组5年总生存率（31.2%）和5年无复发生存率（27.2%）均低于非乙双吗啉治疗组（60.3%，58.9%）和未治疗组（54.6%，51.6%; P < 0.01）。乙双吗啉治疗的患者易发生非复发性染色体畸变，缓解率低，预后差。
The association between psoriasis and leukemia is a controversial topic. One hundred acute leukemia (AL) patients with psoriasis were divided into three groups according to treatment of psoriasis: (i) a bimolane treatment group (n = 35); (ii) a nonbimolane treatment group (n = 45); and (iii) an untreated group (n = 20). The most common type of leukemia associated with psoriasis was acute promyelocytic leukemia (APL). The proportion of nonrecurrent clonal chromosome structural aberration in the bimolane treatment group (42.9%) was significantly higher than that of the nonbimolane treatment group (17.1%) and the untreated group (21.4%; P < 0.05). In patients with non-APL, the complete remission rate of the first course in the nonbimolane treatment group (84.2%) was significantly higher than that of the bimolane treatment group (8.3%) and the untreated group (37.5%; P < 0.05). The 5-year overall survival rate (31.2%) and 5-year relapse-free survival rate (27.2%) in the bimolane group were lower than those of the nonbimolane treatment group (60.3%, 58.9%) and the untreated group (54.6%, 51.6%; P < 0.01). Nonrecurrent chromosome aberration (CA) was prone to occur in bimolane treated patients, who have lower remission rates and poor prognoses.
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影响因子：
3.7
作者：
Charles PE;Ladoire S;Aho S;Quenot JP;Doise JM;Prin S;Olsson NO;Blettery B
通讯作者：
Blettery B
影响因子：
6.5
作者：
Y. Kwong;CK Lam;T. M. Chan
通讯作者：
Y. Kwong;CK Lam;T. M. Chan
DOI：
--
发表时间：
2008-12
期刊：
Prilozi
影响因子：
--
作者：
I. Panovska-Stavridis;L. Cevreska;M. Ivanovski;A. Stojanovik;M. Lozance;N. Matevska;Aleksandar S. Dimovski;Serafimoski
通讯作者：
I. Panovska-Stavridis;L. Cevreska;M. Ivanovski;A. Stojanovik;M. Lozance;N. Matevska;Aleksandar S. Dimovski;Serafimoski
DOI：
10.1007/springerreference_110015
发表时间：
2004
期刊：
Indian journal of medical sciences
影响因子：
--
作者：
A. Shah
通讯作者：
A. Shah
影响因子：
1.1
作者：
Francois, Dominique;Trigui, Nawel;de Mazancourt, Philippe
通讯作者：
de Mazancourt, Philippe