Image registration for targeted MRI-guided transperineal prostate biopsy
Image registration for targeted MRI-guided transperineal prostate biopsy
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DOI：
10.1002/jmri.23688
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发表时间：
2012-10-01
影响因子：
4.4
通讯作者：
Tempany, Clare M.
中科院分区：
文献类型：
--
作者：
Fedorov, Andriy;Tuncali, Kemal;Tempany, Clare M.
目的：开发并评价MR引导下经会阴前列腺穿刺活检过程中自动重新识别术前MR检查中可疑肿瘤病灶的图像配准方法。材料与方法：开发了一种用于计划和术中T2加权前列腺MRI之间自动配准的分层方法，并在10次连续MR引导活检期间采集的图像上进行了评价。在基于图像的标志处并通过评估手动分割的前列腺和子结构的空间重叠来量化配准精度。通过模拟初始误配准和分析收敛行为来评估配准的可靠性。在计划的活检靶点处表征配准精度。结果如下：总的计算时间是兼容的临床设置，最多2分钟。变形登记导致一个显着改善的空间重叠的前列腺和外周区轮廓相比，刚性和仿射登记。平均切片标志配准误差为1.3 +/- 0.5 mm. Experiments模拟初始误配准导致估计的平均捕获范围为6 mm，平均切片配准精度为+/-0.3 mm. Conclusion：我们的配准方法需要最少的用户交互，并与我们的介入临床工作流程的时间限制兼容。初步评价表明，该方法的准确度、可靠性和一致性可接受。J.磁共振Imaging 2012;36：987992. (c)2012 Wiley Periodicals，Inc.
Purpose: To develop and evaluate image registration methodology for automated re-identification of tumor-suspicious foci from preprocedural MR exams during MR-guided transperineal prostate core biopsy. Materials and Methods: A hierarchical approach for automated registration between planning and intra-procedural T2-weighted prostate MRI was developed and evaluated on the images acquired during 10 consecutive MR-guided biopsies. Registration accuracy was quantified at image-based landmarks and by evaluating spatial overlap for the manually segmented prostate and sub-structures. Registration reliability was evaluated by simulating initial mis-registration and analyzing the convergence behavior. Registration precision was characterized at the planned biopsy targets. Results: The total computation time was compatible with a clinical setting, being at most 2 min. Deformable registration led to a significant improvement in spatial overlap of the prostate and peripheral zone contours compared with both rigid and affine registration. Average in-slice landmark registration error was 1.3 +/- 0.5 mm. Experiments simulating initial mis-registration resulted in an estimated average capture range of 6 mm and an average in-slice registration precision of +/-0.3 mm. Conclusion: Our registration approach requires minimum user interaction and is compatible with the time constraints of our interventional clinical workflow. The initial evaluation shows acceptable accuracy, reliability and consistency of the method. J. Magn. Reson. Imaging 2012;36:987992. (c) 2012 Wiley Periodicals, Inc.