Association of attention deficit hyperactivity disorder and gestational alcohol exposure: an exploratory study.

Association of attention deficit hyperactivity disorder and gestational alcohol exposure: an exploratory study.
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DOI:
10.1177/1087054705283880
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发表时间:
2006-02-01
影响因子:
3
通讯作者:
Ellis, Roland
Ellis, Roland
中科院分区:
医学2区
文献类型:
--
作者:
Bhatara, Vinod;Loudenberg, Roland;Ellis, Roland

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目的和方法:为了探讨 ADHD 患病率与妊娠期酒精暴露风险水平之间的关联,作者回顾了 2,231 名因胎儿酒精谱系障碍转诊的青少年的图表。根据妊娠期酒精暴露风险的不同程度,参与者被分为四组。对于每组,都确定了 ADHD 和其他选定疾病的患病率。 结果:总体患病率中排名第一的疾病是 ADHD (41%),其次是学习障碍 (17%) 和对立违抗/品行障碍 (16%)。各组 ADHD 患病率一般为高风险 > 有风险 > 未知风险 > 无风险。结论:ADHD 病例的频率分布取决于妊娠期酒精暴露的风险水平。这些结果为支持多动症与产前酒精暴露之间的关联提供了越来越多的证据。研究结果需要通过关于多动症和妊娠期酒精暴露的明确研究来证实。
OBJECTIVE AND METHODS: To explore association between prevalence of ADHD and levels of risk for gestational alcohol exposure, the authors reviewed the charts of 2,231 youth referred for fetal alcohol spectrum disorders. Participants were categorized into four groups by different levels of risk for gestational alcohol exposure. For each group, the prevalence rates of ADHD and other selected disorders were determined.RESULTS: The disorder ranking first in overall prevalence was ADHD (41%), followed by learning disorder (17%) and oppositional-defiant/conduct disorder (16%). Prevalence rates of ADHD across the groups generally were high risk > some risk > unknown risk > no risk.CONCLUSION: The frequency distribution of ADHD cases was according to the levels of risk for gestational alcohol exposure. These results add to a growing body of evidence supporting an association between ADHD and prenatal alcohol exposure. Findings need to be confirmed by definitive studies on ADHD and gestational alcohol exposure.