Recurrence After Endoscopic Mucosal Resection for Superficial Esophageal Cancer
Recurrence After Endoscopic Mucosal Resection for Superficial Esophageal Cancer
复制标题
浅表食管癌内镜粘膜切除术后复发
DOI：
10.1055/s-2000-7379
复制
发表时间：
2000
期刊：
影响因子：
9.3
通讯作者：
S. Yoshida
中科院分区：
文献类型：
--
作者：
T. Nomura;N. Boku;A. Ohtsu;M. Muto;S. Matsumoto;H. Tajiri;S. Yoshida
背景与研究目的
BACKGROUND AND STUDY AIMS
We present the results of endoscopic mucosal resection (EMR) for superficial esophageal cancer in patients treated at the National Cancer Center Hospital East since March 1993, and discuss the factors involved in local recurrence.
PATIENTS AND METHODS
The study consisted of 51 patients with a total of 57 superficial esophageal cancers which were treated by EMR at the National Cancer Center Hospital East between March 1993 and March 1998. EMR was performed with a two-channel fiberscope or with the assistance of the endoscopic esophageal mucosal resection tube. Follow-up examinations by means of endoscopy with iodine staining and biopsy were repeated every 3-6 months.
RESULTS
A total of 19 patients had double cancers; 12 had head and neck cancers (HNC), six had stomach cancers, and one had lung cancer. The patients with HNC tended to have multiple iodine-unstained areas, and multiple cancers in the esophagus. Local recurrence was detected in two out of five patients (40%) with multiple esophageal cancers, and in two out of 46 patients (4%) with solitary cancer (P=0.0433). There was no difference in the rate of local recurrence between patients with HNC and those without HNC. Three out of four patients with recurrent cancers were given additional treatment, EMR for two and radiotherapy alone for one; no further recurrence occurred except in the patient who underwent radiotherapy alone.
CONCLUSIONS
Multiplicity of cancer is a risk factor for local recurrence. Appropriate additional treatment should be indicated for recurrent lesions.