Preventing hepatitis B though universal vaccination: Reduction of inequalities through the GAVI China project
Preventing hepatitis B though universal vaccination: Reduction of inequalities through the GAVI China project
复制标题
DOI：
10.1016/j.vaccine.2012.07.048
复制
发表时间：
2013-12-27
期刊：
影响因子：
5.5
通讯作者：
Yang, Weizhong
中科院分区：
文献类型：
--
作者：
Cui, Fuqiang;Liang, Xiaofeng;Yang, Weizhong
目的：衡量全球疫苗免疫联盟项目资助的贫困县乙肝覆盖率以及贫困地区乙肝防治平等进展情况。方法：回顾常规报告的覆盖率数据，并根据世界卫生组织推荐的抽样方法，于2010年10月进行了全国分层、验证、横断面调查。首先，我们根据经济标准将中国分为三个区域（东部、中部和西部）。其次，在每个地区，我们按照与人口规模成比例的概率选择了八个县。第三，在每个选定的县中，我们在该县的乡镇名单中随机抽取了10个乡镇。结果：作为最终评估的一部分，我们访问了244个乡镇（东部71个，中部86个，西部87个）。总体而言，在这 244 个乡镇，TBD 调查覆盖率从 2002 年的 60% 上升到 2009 年的 91%，乙肝疫苗三剂调查覆盖率从 2002 年的 71% 上升到 2009 年的 93%。 总体而言，在 GAVI 支持的地区，HepB3/DTP3 比率从 2002 年的 57% 上升到 2009 年的 94%。 2009.结论：全球疫苗和免疫联盟的扶贫方法是通过提供免费疫苗接种减少儿童不平等的有效方法。当免费提供疫苗和AD注射器时，缩小了东西部地区、贫富之间的差距。 (C) 2012 Elsevier Ltd. 保留所有权利。
Objective: In order to measure hepatitis B coverage and progress in equality with respect to protection against hepatitis B in poverty-affected areas funded by the Global Alliance on Vaccine and Immunization project funded in poverty-affected counties.Methods: We reviewed routinely reported coverage data and conducted a national stratified, validation, cross-sectional survey in October 2010, according to WHO recommended sampling method. First, we stratified China into three regions (Eastern, Central and Western) based on economic criteria. Second, in each region, we selected eight counties with a probability proportional to population size. Third, in each selected county, we selected (a) 10 townships at random among the list of townships of the county.Results: We visited 244 townships as part of the final evaluation (71 in the East, 86 in the Center and 87 in the West). Overall, in these 244 townships, surveyed TBD coverage increased from 60% in 2002 to 91% in 2009 and surveyed three dose of hepatitis B vaccine coverage increased from 71% in 2002 to 93% in 2009. Overall, in the GAVI supported areas, the HepB3/DTP3 ratio increased from 57% in 2002 to 94% in 2009.Conclusion: Pro-poor GAVI approach was an effective way to reduce inequity among children through provision of free vaccination. When vaccine and AD syringes were provided for free, they closed the gap between Eastern and Western regions and between the rich and the poor. (C) 2012 Elsevier Ltd. All rights reserved.