5-S-cysteinyldopa excretion after treatment with 8-methoxypsoralen and UVA light.

5-S-cysteinyldopa excretion after treatment with 8-methoxypsoralen and UVA light.
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8-甲氧基补骨脂素和 UVA 光处理后 5-S-半胱氨酰多巴的排泄。

DOI:
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发表时间:
1978
影响因子:
6.5
通讯作者:
Eva. Tegner
Eva. Tegner
中科院分区:
医学1区
文献类型:
--
作者:
G. Agrup;Christer Hansson;Hans Rorsman;Anna;Evald Rosengren;Eva. Tegner

文献摘要

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研究了8-甲氧基补骨脂素和UVA光治疗银屑病患者特异性黑素细胞代谢物5- s -半胱氨酸多巴的排泄。治疗2天后发现明显增加,但尚未观察到色素沉着增加。尿5- s -半胱氨酸多巴在治疗1或2周后出现峰值。5- s -半胱氨酸多巴排泄达到最大值后,色素沉着持续增加。
The excretion of the specific melanocytic metabolite 5-S-cysteinyldopa was studied in patients with psoriasis treated by 8-methoxypsoralen and UVA light. A pronounced increase was found after only 2 days treatment, although no increase in pigmentation could yet be observed. Peak values for urinary 5-S-cysteinyldopa were noted after 1 or 2 weeks treatment. Increase in pigmentation persisted after the excretion maxima for 5-S-cysteinyldopa.