Kinetic Resolution of Racemic α-Hydroxyphosphonates by Asymmetric Esterification Using Achiral Carboxylic Acids with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst
Kinetic Resolution of Racemic α-Hydroxyphosphonates by Asymmetric Esterification Using Achiral Carboxylic Acids with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst
复制标题
使用非手性羧酸与新戊酸和手性酰基转移催化剂进行不对称酯化反应动力学拆分外消旋 α-羟基膦酸酯
DOI：
10.1039/c3cc44293d
复制
发表时间：
2013
影响因子：
4.9
通讯作者：
T. Nakahara
中科院分区：
文献类型：
--
作者：
I. Shiina;K. Ono;T. Nakahara
A practical protocol is developed to directly provide chiral α-acyloxyphosphonates and α-hydroxyphosphonates from (±)-α-hydroxyphosphonates utilizing the transacylation process to generate the mixed anhydrides from acid components and pivalic anhydride in the presence of organocatalysts (s-value = 33–518).
