Design of Heterogeneous Nuclei for Lateral Crystallization via Uniaxial Assembly of Cellulose Nanocrystals
Design of Heterogeneous Nuclei for Lateral Crystallization via Uniaxial Assembly of Cellulose Nanocrystals
复制标题
通过纤维素纳米晶体单轴组装横向结晶的异质核设计
DOI：
10.1021/acs.cgd.6b00707
复制
发表时间：
2016-08-01
影响因子：
3.8
通讯作者：
Liu, Xiang Yang
中科院分区：
文献类型：
--
作者：
Lu, Zihao;Qi, Xiaoqing;Liu, Xiang Yang
半结晶聚合物是一类廉价的非均质结晶晶核。然而，纤维素，最丰富的生物SCP，是臭名昭著的，其加工性能差。这限制了它作为功能化合物结晶取向导向剂的应用。不同于目前聚合物工程方法的单轴SCP薄膜，我们探索了一种新的方法，单轴纤维素薄膜通过定向组装的纤维素纳米晶体（CNCs）通过一个简单的浸涂技术。该薄膜成功地引导了两种药物化合物的横向结晶，这反过来反映了宏观尺度上单轴CNC对齐的均匀性。此外，不同于传统的SCP薄膜，由不同的外力驱动的组装路线可以导致CNC薄膜具有不同的取向特性，用于制造图案化的药物薄膜。新兴的胶体组装路线的单轴SCP基板LE…
Semicrystalline polymers (SCPs) represent a group of cheap heterogeneous nuclei for crystallization. Nevertheless, cellulose, the most abundant biogenic SCP, is notorious for its poor processability. This limits its application as the orientational guiding agent in crystallization of functional compounds. Different from current polymer engineering approaches to uniaxial SCP thin films, we explored a novel approach to the uniaxial cellulose thin film via the oriented assembly of cellulose nanocrystals (CNCs) by means of a simple dip-coating technique. This thin film successfully guides the lateral crystallization of two drug compounds, which in turn reflects the uniformity of the uniaxial CNC alignment on the macroscopic scale. Furthermore, unlike traditional SCP thin films, the assembly route driven by different external forces can lead to CNC thin films with distinct orientational characters for fabrication of patterned drug thin films. The emerging colloidal assembly route to a uniaxial SCP substrate le...