Neural crest derivatives in ocular and periocular structures
Neural crest derivatives in ocular and periocular structures
复制标题
DOI：
10.1387/ijdb.041937sc
复制
发表时间：
2005-01-01
影响因子：
0.7
通讯作者：
Couly, GR
中科院分区：
文献类型：
--
作者：
Creuzet, S;Vincent, C;Couly, GR
在脊椎动物中，眼睛是一种外胚层复合结构，结合了神经外胚层和基板原基。此外，它早期受益于间充质外胚层衍生的成分，神经嵴。在这方面，鹌鹑和小鸡之间的嵌合体的建设一直是一个转折点，有助于评估的贡献，头神经嵴的发展，眼睛和眼周结构。鉴于各种各样的波峰衍生物强调在发展中的眼睛，这项研究说明了迷人的能力，这种独特的结构，以精细地适应其分化的微环境线索。神经嵴细胞对眼发育的贡献的分析强调了它们在设计眼前段、提供屈光介质和促进前视房的同源性方面的重要作用。
In vertebrates, the eye is an ectodermal compound structure associating neurectodermal and placodal anlagen. In addition, it benefits early on from a mesenchymal ectoderm -derived component, the neural crest. In this respect, the construction of chimeras between quail and chick has been a turning point, instrumental in appraising the contribution of the cephalic neural crest to the development of ocular and periocular structures. Given the variety of crest derivatives underscored in the developing eye,this study illustrates the fascinating ability of this unique structure to finely adapt its differentiation to microenvironmental cues. This analysis of neural crest cell contribution to ocular development emphasizes their paramount role to design the anterior segment of the eye, supply refracting media and contribute to the homeostasy of the anterior optic chamber.