Skipping ahead: A circuit for representing the past, present, and future.
Skipping ahead: A circuit for representing the past, present, and future.
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DOI：
10.7554/elife.68795
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发表时间：
2021-10-14
期刊：
影响因子：
7.7
通讯作者：
Brandon MP
中科院分区：
文献类型：
--
作者：
Robinson JC;Brandon MP
展望未来与我们记忆过去的能力有着直观的联系。在记忆系统中，大量的研究表明，前额叶皮层和海马体参与了对过去和现在的记忆。最近的数据表明，前额皮质和海马体都对未来的轨迹进行编码，这些轨迹在时间上被θ节律的交替周期所分隔。在这里，我们将讨论信息是如何在时间上组织这些大脑区域的内侧隔，核reuniens和海马旁区域的支持。最后，我们强调了一个大脑回路，我们预测是必不可少的时间隔离的未来的情况。
Envisioning the future is intuitively linked to our ability to remember the past. Within the memory system, substantial work has demonstrated the involvement of the prefrontal cortex and the hippocampus in representing the past and present. Recent data shows that both the prefrontal cortex and the hippocampus encode future trajectories, which are segregated in time by alternating cycles of the theta rhythm. Here, we discuss how information is temporally organized by these brain regions supported by the medial septum, nucleus reuniens, and parahippocampal regions. Finally, we highlight a brain circuit that we predict is essential for the temporal segregation of future scenarios.