The shape of the aging human lens: curvature, equivalent refractive index and the lens paradox
The shape of the aging human lens: curvature, equivalent refractive index and the lens paradox
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DOI：
10.1016/s0042-6989(01)00057-8
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发表时间：
2001-06-01
期刊：
影响因子：
1.8
通讯作者：
Van der Heijde, GL
中科院分区：
文献类型：
--
作者：
Dubbelman, M;Van der Heijde, GL
晶体透镜的Scheimpflug狭缝图像由于角膜的折射特性并且因为它们被倾斜地观看而失真。我们测量了102名年龄在16岁至65岁之间的受试者的透镜的非球面曲率，并对这些畸变进行了校正。通过测量人工眼和具有已知尺寸的人工晶状体的人工晶状体患者来验证该过程。与先前使用Scheimpflug摄影的研究相比，前透镜表面半径随年龄的减小较小，前和后透镜表面半径的绝对值显著较小。可以证明后透镜半径随年龄的增长而轻微减小。一般来说，正面和背面是双曲线的。测量了42名受试者的眼轴长度：能够计算透镜的等效折射率，其显示出随着年龄的增长而小幅但非常显著的降低。这些新发现解释了透镜悖论，并可能作为透镜折射特性建模的基础。(C)2001爱思唯尔科技有限公司版权所有。
Scheimpflug slit images of the crystalline lens are distorted due to the refracting properties of the cornea and because they are obliquely viewed. We measured the aspheric curvature of the lens of 102 subjects ranging in age between 16 and 65 years and applied correction for these distortions. The procedure was validated by measuring an artificial eye and pseudophakic patients with intraocular lenses of known dimensions. Compared to previous studies using Scheimpflug photography, the decrease of the radius of the anterior lens surface with age was smaller, and the absolute value for the radius of the anterior and posterior lens surface was significantly smaller. A slight decrease of the posterior lens radius with age could be demonstrated. Generally, front and back surfaces were hyperbolic. Axial length was measured of 42 subjects: enabling calculation of the equivalent refractive index of the lens, which showed a small, but highly significant decrease with age. These new findings explain the lens paradox and may serve as a basis for modelling the refractive properties of the lens. (C) 2001 Elsevier Science Ltd. All rights reserved.