Dietary Glycemic Index, Glycemic Load and Blood Lipid Levels in Middle-Aged Japanese Men and Women
Dietary Glycemic Index, Glycemic Load and Blood Lipid Levels in Middle-Aged Japanese Men and Women
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DOI：
10.5551/jat.4101
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发表时间：
2010-01-01
影响因子：
4.4
通讯作者：
Nakagawa, Hideaki
中科院分区：
文献类型：
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作者：
Nakashima, Motoko;Sakurai, Masaru;Nakagawa, Hideaki
目的：本研究调查了日本中年男性和女性的饮食血糖指数（GI）/血糖负荷（GL）与血脂之间的关系。方法：研究参与者是日本一家金属制品厂的员工：2，257名男性和1，598名女性，年龄在35岁以上。使用自填饮食史问卷评估饮食GI和GL。血脂水平，调整年龄，体重指数，饮酒，吸烟，体力活动，绝经状态，总能量，饱和脂肪酸，单不饱和脂肪酸，多不饱和脂肪酸，胆固醇和纤维的饮食摄入量，GI/GL五分位数之间进行了比较，为每个gender.Results：没有显着的关联，观察到GI和调整血脂之间的男性或女性。相反，GL与HDL-胆固醇在男性和女性中呈负相关（男性趋势p =0.001，女性< 0.001），与非HDL胆固醇呈正相关（趋势p =0.010），LDL-胆固醇（趋势p =0.035）和甘油三酯（p =0.011）;然而，饮酒影响了这些关联;男性不饮酒者的GL与血脂无相关性，女性不饮酒者的GL与LDL-胆固醇无相关性。在日本女性中，GL与HDL-胆固醇呈负相关，与非HDL-胆固醇呈正相关。在不饮酒的人身上没有观察到这些关联。女性高GL饮食可能通过这些血脂异常产生致动脉粥样硬化作用。
Aims: This study investigated the association between dietary glycemic index (GI)/glycemic load (GL) and serum lipids in middle-aged Japanese men and women.Methods: The study participants were employees of a metal products factory in Japan: 2,257 men and 1,598 women aged 35 years or older. Dietary GI and GL were assessed using a self-administered diet history questionnaire. Serum lipid levels, adjusted for age, body mass index, alcohol consumption, smoking, physical activity, menopause status, and dietary intake of total energy, saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, cholesterol and fiber, were compared among GI/GL quintiles for each gender.Results: No significant associations were observed between GI and adjusted serum lipids in men or women. In contrast, GL was inversely associated with HDL-cholesterol in men and women (p for trend=0.001 for men and < 0.001 for women), and positively associated with non-HDL-cholesterol (p for trend=0.010), LDL-cholesterol (p for trend=0.035) and triglycerides (p for trend=0.011) in women; however, alcohol drinking affected these associations; there was no association between GL and serum lipids in male nondrinkers and between GL and LDL-cholesterol in female nondrinkers.Conclusion: GL was inversely associated with HDL-cholesterol and positively associated with non-HDL-cholesterol in Japanese women. These associations in men were not observed in nondrinkers. A high-GL diet for women may have an atherogenic effect through these serum lipid abnormalities.