MIPS: a database for genomes and protein sequences
MIPS: a database for genomes and protein sequences
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DOI：
10.1093/nar/27.1.44
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发表时间：
1999-01-01
影响因子：
14.9
通讯作者：
Frishman, D
中科院分区：
文献类型：
--
作者：
Mewes, HW;Heumann, K;Frishman, D
位于德国慕尼黑附近 Martinsried 的慕尼黑蛋白质序列信息中心 (MIPS-GSF) 开发和维护面向基因组的数据库。可用的序列数据量迅速增加是很常见的，但序列数据库中合格的手动注释的能力却没有增加。因此，我们的策略旨在通过对完整基因组序列的分析工具的综合应用、对蛋白质序列的系统分类以及对序列分析和功能基因组学项目的积极支持来应对数据流。本报告介绍了基因组的系统和最新分析（PEDANT）、酵母基因组综合数据库（MYGD）、反映拟南芥测序进展的数据库 基因组 (MATD)、组装、注释的人类 EST 簇 (MEST) 数据库以及 PIR-国际蛋白质序列数据库框架内的蛋白质序列数据集合（在本卷其他部分进行了描述）。 MIPS 通过其 WWW 服务器 (http://www.mips.biochem.mpg.de) 提供对一系列通用数据库的访问，包括上述数据库以及蛋白质家族数据库 (PROTFAM)、MITOP 数据库和 all-against-all PASTA 数据库。
The Munich Information Center for Protein Sequences (MIPS-GSF), Martinsried near Munich, Germany, develops and maintains genome oriented databases. It is commonplace that the amount of sequence data available increases rapidly, but not the capacity of qualified manual annotation at the sequence databases. Therefore, our strategy aims to cope with the data stream by the comprehensive application of analysis tools to sequences of complete genomes, the systematic classification of protein sequences and the active support of sequence analysis and functional genomics projects, This report describes the systematic and up-to-date analysis of genomes (PEDANT), a comprehensive database of the yeast genome (MYGD), a database reflecting the progress in sequencing the Arabidopsis thaliana genome (MATD), the database of assembled, annotated human EST clusters (MEST), and the collection of protein sequence data within the framework of the PIR-International Protein Sequence Database (described elsewhere in this volume). MIPS provides access through its WWW server (http://www.mips.biochem.mpg.de) to a spectrum of generic databases, including the above mentioned as well as a database of protein families (PROTFAM), the MITOP database, and the all-against-all PASTA database.