Flap Prefabrication and Stem Cell–Assisted Tissue Expansion: How We Acquire a Monoblock Flap for Full Face Resurfacing

Flap Prefabrication and Stem Cell–Assisted Tissue Expansion: How We Acquire a Monoblock Flap for Full Face Resurfacing
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DOI:
10.1097/01.scs.0000436743.75289.6b
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发表时间:
2014-01
影响因子:
0.9
通讯作者:
Qingfeng Li;T. Zan;Haizhou Li;Shuangbai Zhou;B. Gu;Kai Liu;F. Xie;Yun Xie
Qingfeng Li;T. Zan;Haizhou Li;Shuangbai Zhou;B. Gu;Kai Liu;F. Xie;Yun Xie
中科院分区:
医学4区
文献类型:
--
作者:
Qingfeng Li;T. Zan;Haizhou Li;Shuangbai Zhou;B. Gu;Kai Liu;F. Xie;Yun Xie

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摘要全脸皮肤软组织缺损是整形外科面临的最大挑战之一。重建整个脸的均匀覆盖和精致的功能是很难实现的。为了避免在多个皮瓣和皮肤移植物中看到的拼凑结果,具有相似颜色,纹理和厚度的1个整体皮瓣可能是最小化切口疤痕和几个外科手术的理想选择,但由于缺乏足够的匹配组织和如此大的皮瓣的不可靠的血液供应,目前的方法无法使用。为了获得一个完整的面部再造的整体皮瓣,我们结合联合收割机的预制皮瓣,皮肤过度扩张,和骨髓单个核干细胞移植的全面部再造。在这篇文章中,我们提出了我们的经验,从我们的案件系列,提供普遍匹配的皮肤和接近正常的面部轮廓。结论:该方法是修复面部大面积皮肤缺损的可靠方法。
AbstractTotal face skin and soft-tissue defects remain one of the biggest challenges in reconstructive surgery. Reconstruction of the entire face with uniform coverage and delicate features is difficult to achieve. To avoid the patchwork result seen in multiple flaps and skin grafts, 1 monoblock flap that has similar color, texture, and thickness might be an ideal option to minimize the incisional scars and several surgical procedures but is unavailable with current approaches because of the lack of sufficient matched tissue and the unreliable blood supply for such a large flap. To acquire a monoblock flap for full face reconstruction, we combine the prefabricated flaps, skin overexpansion, and bone marrow mononuclear stem cell transplantation for total facial resurfacing. In this article, we present our experience from our case series that provides universally matched skin and near-normal facial contour. It is a reliable and an excellent reconstructive option for massive facial skin defect.