Effects of sintering temperature on the compressive mechanical properties of collagen/hydroxyapatite composite scaffolds for bone tissue engineering
Effects of sintering temperature on the compressive mechanical properties of collagen/hydroxyapatite composite scaffolds for bone tissue engineering
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DOI：
10.1016/j.matlet.2016.03.028
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发表时间：
2016-06-15
影响因子：
3
通讯作者：
Todo, Mitsugu
中科院分区：
文献类型：
--
作者：
Islam, Md. Shariful;Todo, Mitsugu
采用模板法制备羟基磷灰石（HA）多孔支架，并采用胶原（COL）或COL/HA颗粒制备。通过改变烧结温度来研究烧结对支架力学性能的影响。研究发现，添加COL或COL/HA颗粒的纯HA支架的制备引入了不同的层或相，使制备的支架得到强化，其力学性能得到改善。此外，较高的烧结温度还可以通过降低孔隙率来提高制备的HA多孔复合材料支架的力学性能。(C) 2016 Elsevier B.V.版权所有
Hydroxyapatite (HA) porous scaffolds were prepared by a template method and fabricated using either collagen (COL) or COL/HA particles. The sintering temperature was varied to discover the sintering effects on the mechanical properties of the scaffold. It was found that fabrication of pure HA scaffolds with COL or COL/HA particles introduced a distinct layer or phase, causing the fabricated scaffolds to be strengthened and their mechanical properties to be improved. Moreover, it was found that higher sintering temperatures also enhanced the mechanical properties of fabricated HA porous composite scaffolds by reducing porosity. (C) 2016 Elsevier B.V. All rights reserved.