Infections with Escherichia coli O157:H7 in Washington State. The first year of statewide disease surveillance.
Infections with Escherichia coli O157:H7 in Washington State. The first year of statewide disease surveillance.
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华盛顿州发生大肠杆菌 O157:H7 感染。
DOI：
10.1001/jama.1989.03430030043031
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
J. Lewis
中科院分区：
文献类型：
--
作者：
S. Ostroff;J. Kobayashi;J. Lewis
1987年，华盛顿成为第一个要求报告O157：H7型大肠杆菌感染的州。在监测的第一年，报告了93例病例，年发病率为每10万人2.1例。病例患者的中位年龄为14岁（范围为11个月至78岁），5岁以下儿童的发病率最高（每年每10万人口中有6.1例）。95%的报告病例出现血性腹泻，12%的患者出现溶血性尿毒症综合征或血栓性血小板减少性紫癜，1例患者死亡。在5%的家庭中发现疑似继发病例。五十六例（60%）病例发生在6月至9月期间，73%的溶血性尿毒症综合征或血栓性血小板减少性紫癜病例也是如此。夏季报告的病例比一年中其他时间报告的病例更有可能发生在10岁以下的儿童中。包括抗菌药物在内的药物不会影响症状的持续时间，也不会改变发生溶血性尿毒综合征或血栓性血小板减少性紫癜的风险。这个在华盛顿新建立的监测系统表明，大肠杆菌O 157：H 7是美国出血性腹泻的一个重要和常见原因。
In 1987, Washington became the first state to require that infection with Escherichia coli serotype O157:H7 be reported. In the first year of surveillance, 93 cases were reported, yielding an annual incidence of 2.1 cases per 100,000 population. The median age of case patients was 14 years (range, 11 months to 78 years), with the highest attack rate among children younger than 5 years (6.1 cases per 100,000 population per year). Bloody diarrhea was present in 95% of reported cases, 12% of patients developed either hemolytic-uremic syndrome or thrombotic thrombocytopenic purpura, and one patient died. Suspected secondary cases were seen in 5% of households. Fifty-six (60%) cases occurred during June through September, as did 73% of the cases of hemolytic-uremic syndrome or thrombotic thrombocytopenic purpura. Cases reported during the summer months were more likely than cases reported at other times of the year to be in children younger than 10 years. Medications, including antimicrobial medications, did not influence the duration of symptoms, nor did they appear to alter the risk of developing hemolytic-uremic syndrome or thrombotic thrombocytopenic purpura. This newly established surveillance system in Washington demonstrates that E coli O157:H7 is an important and common cause of bloody diarrhea in the United States.
大肠杆菌 O157:H7 作为与溶血性尿毒症综合征相关的主要病原体：太平洋西北地区的一项前瞻性研究。
影响因子：
8
作者：
Neill,MA;Tarr,PI;Clausen,CR;Christie,DL;Hickman,RO
通讯作者：
Hickman,RO
大肠杆菌 O157:H7 引起的出血性结肠炎先于成人溶血性尿毒症综合征。
影响因子：
--
作者：
Neill,MA;Agosti,J;Rosen,H
通讯作者：
Rosen,H