Neuroimaging in pediatric traumatic brain injury: current and future predictors of functional outcome.
Neuroimaging in pediatric traumatic brain injury: current and future predictors of functional outcome.
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儿科创伤性脑损伤的神经影像学：当前和未来功能结果的预测因素。
DOI：
10.1002/ddrr.62
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发表时间：
2009
影响因子：
--
通讯作者：
Huisman,ThierryAGM
中科院分区：
文献类型：
--
作者：
Suskauer,StacyJ;Huisman,ThierryAGM
尽管神经影像学长期以来在儿科创伤性脑损伤（TBI）的急性管理中发挥了作用，但直到最近，其作为理解和预测TBI后长期脑行为关系的工具的使用受到常规临床成像检测弥漫性轴索损伤（DAI）的相对较差的灵敏度的限制。新的基于磁共振的成像技术证明了对DAI的灵敏度提高。早期的研究表明，这些技术有望在全球范围内和特定的神经心理学领域内识别慢性功能的成像预测因子和相关因子。在这篇综述中，我们描述了新的，先进的成像技术，包括扩散加权和扩散张量成像，磁敏感加权成像和1H-磁共振波谱的原理。此外，我们总结了目前的研究表明，他们的早期成功建立TBI后的成像措施和功能结果之间的关系。随着正在进行的研究，这些成像技术可以更早地识别每个TBI儿童组织损伤的可能慢性后遗症，从而促进提供成功康复服务的功效和效率。© 2009 Wiley利斯公司Dev Disabil Res Rev 2009;15：117-123。
Although neuroimaging has long played a role in the acute management of pediatric traumatic brain injury (TBI), until recently, its use as a tool for understanding and predicting long‐term brain‐behavior relationships after TBI has been limited by the relatively poor sensitivity of routine clinical imaging for detecting diffuse axonal injury (DAI). Newer magnetic resonance‐based imaging techniques demonstrate improved sensitivity to DAI. Early research suggests that these techniques hold promise for identifying imaging predictors and correlates of chronic function, both globally and within specific neuropsychological domains. In this review, we describe the principles of new, advanced imaging techniques including diffusion weighted and diffusion tensor imaging, susceptibility weighted imaging, and1H‐magnetic resonance spectroscopy. In addition, we summarize current research demonstrating their early success in establishing relationships between imaging measures and functional outcomes after TBI. With the ongoing research, these imaging techniques may allow earlier identification of possible chronic sequelae of tissue injury for each child with TBI, thereby facilitating efficacy and efficiency in delivering successful rehabilitation services. © 2009 Wiley‐Liss, Inc. Dev Disabil Res Rev 2009;15:117–123.