Lack of effect of ovarian denervation on ovulation and pregnancy in the rabbit.
Lack of effect of ovarian denervation on ovulation and pregnancy in the rabbit.
复制标题
卵巢去神经支配对兔子的排卵和妊娠缺乏影响。
DOI：
10.1016/s0015-0282(16)41474-3
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发表时间：
1975
影响因子：
6.7
通讯作者：
E. Wallach
中科院分区：
文献类型：
--
作者：
S. Weiner;K. Wright;E. Wallach
用卵巢动脉剥离法切断雌性兔一侧卵巢神经，3天内排卵和妊娠。三周后，在重复剖腹手术时，记录卵巢大小、黄体数量和妊娠情况。荧光组织化学研究证实，在五只兔子的卵巢中完全失去了肾上腺素能神经。正常对照侧与失神经支配侧相比，卵巢大小、黄体数目、妊娠数、黄体过剩数均无显著差异。对照侧平均5个黄体/卵巢，邻近子宫角平均3.4个胚胎，失神经侧分别为5个和3.2个。虽然这些发现表明中枢神经传出控制在兔交配后妊娠的发生中不是必不可少的，但我们讨论了卵巢神经肌肉机制在这些功能中的潜在意义，并对未来的研究提出了建议。
Following unilateral ovarian denervation by ovarian artery stripping in female rabbits, ovulation and pregnancy were achieved within 3 days of denervation. Three weeks later, at repeat laparotomy, ovarian dimensions and the numbers of corpora lutea and pregnancies were noted. Fluorescent histochemical studies confirmed complete adrenergic denervation in five of the rabbits' ovaries. There was no significant difference in ovarian dimensions, numbers of corpora lutea and pregnancies, or the excess of corpora lutea over implantations when the intact control side was compared with the denervated side. The control ovaries demonstrated an average of 5 corpora lutea/ovary and an average of 3.4 conceptuses in the adjacent uterine horn, while the numbers on the denervated side were 5 and 3.2, respectively. Although these findings demonstrate that central neural efferent control is not essential for the occurrence of pregnancy after mating in the rabbit, the potential significance of ovarian neuromuscular mechanisms in these functions is discussed, and future studies are suggested.