Increasing prevalence of gestational diabetes mellitus in Chinese women from 1999 to 2008
Increasing prevalence of gestational diabetes mellitus in Chinese women from 1999 to 2008
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DOI：
10.1111/j.1464-5491.2010.03205.x
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发表时间：
2011-06-01
影响因子：
3.5
通讯作者：
Hu, G.
中科院分区：
文献类型：
--
作者：
Zhang, F.;Dong, L.;Hu, G.
目的了解天津市1999-2008年妊娠期糖尿病患病率的变化趋势。方法自1998年起，天津市将妊娠期糖尿病筛查作为产前保健的重要组成部分。1998年12月至2008年12月期间，共有105 473名居住在中国天津六个城区的孕妇参加了妊娠期糖尿病筛查计划。筛选试验包括50-g 1-h葡萄糖试验。在初始筛选时葡萄糖阅读>= 7.8 mmol/l的妇女被邀请接受标准的2小时口服葡萄糖耐量试验，葡萄糖负荷为75 g。妊娠期糖尿病确诊使用世界卫生组织的诊断标准。结果调整后的妊娠期糖尿病患病率在1999-2008年增加了2.8倍，从2.4%增加到6.8%（P < 0.0001的线性趋势）。2008年，30-34岁妇女的妊娠糖尿病年龄别流行率最高（11.3%），25岁及以下妇女最低（1.2%）。35岁及以上女性的患病率为5.3%。结论妊娠期糖尿病在中国城市女性人群中的患病率明显上升，已成为中国重要的公共卫生问题。
P>AimsTo investigate the trend in the prevalence of gestational diabetes mellitus during 1999-2008 in women living in urban Tianjin, China.MethodsA universal screening for gestational diabetes mellitus has become an integral part of the antenatal care in Tianjin, China from 1998. A total of 105 473 pregnant women living in the six urban districts of Tianjin, China, participated in the gestational diabetes mellitus screening programme between December 1998 and December 2008. The screening test consisted of a 50-g 1-h glucose test. Women who had a glucose reading >= 7.8 mmol/l at the initial screening were invited to undergo the standard 2-h oral glucose tolerance test with a 75-g glucose load. Gestational diabetes mellitus was confirmed using the World Health Organization's diagnostic criteria.ResultsThe adjusted prevalence of gestational diabetes mellitus increased by 2.8 times during 1999-2008, from 2.4 to 6.8% (P < 0.0001 for linear trend). In 2008, the age-specific prevalence of gestational diabetes mellitus was the highest among women aged 30-34 years (11.3%) and lowest among women aged 25 and under (1.2%). In women aged 35 years and more, the prevalence was 5.3%.ConclusionsThe prevalence of gestational diabetes mellitus has markedly been increasing in a universally screened urban Chinese female population and has become an important public health problem in China.