Microwave-assisted synthesis of pinacol boronates from aryl chlorides catalyzed by a palladium/imidazolium salt system
Microwave-assisted synthesis of pinacol boronates from aryl chlorides catalyzed by a palladium/imidazolium salt system
复制标题
DOI：
10.1021/ol0171463
复制
发表时间：
2002-02-21
期刊：
影响因子：
5.2
通讯作者：
Seidel, G
中科院分区：
文献类型：
--
作者：
Fürstner, A;Seidel, G
在由 Pd(OAc)(2) 和氯化咪唑鎓 2 原位形成的催化剂存在下，带有吸电子基团的芳基氯与双（频哪醇）硼烷 1 反应，以良好至优异的收率生成芳基硼酸酯。在微波加热下进行时，该反应大大加速。
Aryl chlorides bearing electron-withdrawing groups react with bis(pinacol)borane 1 to give aryl boronates in good to excellent yields in the presence of a catalyst formed in situ from Pd(OAc)(2) and the imidazolium chloride 2. The reaction is greatly accelerated when carried out under microwave heating.