Tetrapyrrole Metabolism in Arabidopsis thaliana.
Tetrapyrrole Metabolism in Arabidopsis thaliana.
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DOI：
10.1199/tab.0145
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发表时间：
2011-01-01
期刊：
影响因子：
--
通讯作者：
Masuda, Tatsuru
中科院分区：
文献类型：
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作者：
Tanaka, Ryouichi;Kobayashi, Koichi;Masuda, Tatsuru
高等植物产生四类四吡咯，即叶绿素（Chl）、血红素、铁血红素和光敏色素。在植物中，四吡咯在包括光合作用、呼吸作用和氮/硫同化在内的广泛生物活动中起着至关重要的作用。所有四类四吡咯都来源于驻留在质体中的共同生物合成途径。在这篇文章中，我们概述了拟南芥和其他高等植物的四吡咯代谢，并描述了所有已确定的参与这种代谢的酶的步骤。本文还综述了Chl生物合成和Chl分解的最新研究进展。该领域的最新进展，特别是对新酶的遗传和生化分析，促使我们重新绘制四吡咯代谢途径。此外，我们还总结了目前对四吡咯代谢调控机制的认识。讨论了四吡咯生物合成与其他细胞过程的相互作用，包括质体到细胞核的信号转导。
Higher plants produce four classes of tetrapyrroles, namely, chlorophyll (Chl), heme, siroheme, and phytochromobilin. In plants, tetrapyrroles play essential roles in a wide range of biological activities including photosynthesis, respiration and the assimilation of nitrogen/sulfur. All four classes of tetrapyrroles are derived from a common biosynthetic pathway that resides in the plastid. In this article, we present an overview of tetrapyrrole metabolism in Arabidopsis and other higher plants, and we describe all identified enzymatic steps involved in this metabolism. We also summarize recent findings on Chl biosynthesis and Chl breakdown. Recent advances in this field, in particular those on the genetic and biochemical analyses of novel enzymes, prompted us to redraw the tetrapyrrole metabolic pathways. In addition, we also summarize our current understanding on the regulatory mechanisms governing tetrapyrrole metabolism. The interactions of tetrapyrrole biosynthesis and other cellular processes including the plastid-to-nucleus signal transduction are discussed.