Plant circadian rhythms regulate the effectiveness of a glyphosate-based herbicide
Plant circadian rhythms regulate the effectiveness of a glyphosate-based herbicide
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DOI：
10.1038/s41467-019-11709-5
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发表时间：
2019-08-16
影响因子：
16.6
通讯作者：
Dodd, Antony N.
中科院分区：
文献类型：
--
作者：
Belbin, Fiona E.;Hall, Gavin J.;Dodd, Antony N.
除草剂通过控制杂草和管理收割来增加作物产量。草甘膦是使用最广泛的除草剂活性成分，每年在全球3.5亿公顷的含草甘膦产品上花费110亿美元，使用约86亿公斤草甘膦。草甘膦的除草效果取决于喷洒的时间。在这里，我们展示了植物生物钟调节草甘膦的有效性。我们发现，由于草甘膦活性、昼夜节律振荡器和潜在的生长素信号之间的相互作用，草甘膦抑制植物发育具有每日和昼夜节律。我们发现生物钟控制着草甘膦诱导植物细胞死亡的时间和程度。此外，时钟控制着草甘膦最小有效剂量的节奏。我们提出了农业时间疗法的概念，在原理上类似于医疗实践中的时间疗法。我们的发现为改进农用化学品的使用和开发提供了一个平台，并带来了未来的经济和环境效益。
Herbicides increase crop yields by allowing weed control and harvest management. Glyphosate is the most widely-used herbicide active ingredient, with $11 billion spent annually on glyphosate-containing products applied to >350 million hectares worldwide, using about 8.6 billion kg of glyphosate. The herbicidal effectiveness of glyphosate can depend upon the time of day of spraying. Here, we show that the plant circadian clock regulates the effectiveness of glyphosate. We identify a daily and circadian rhythm in the inhibition of plant development by glyphosate, due to interaction between glyphosate activity, the circadian oscillator and potentially auxin signalling. We identify that the circadian clock controls the timing and extent of glyphosate-induced plant cell death. Furthermore, the clock controls a rhythm in the minimum effective dose of glyphosate. We propose the concept of agricultural chronotherapy, similar in principle to chronotherapy in medical practice. Our findings provide a platform to refine agrochemical use and development, conferring future economic and environmental benefits.